STAT3-IN-1 Inhibitor

Name: STAT3-IN-1 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5753970
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5753970

STAT3-IN-1 selective and orally active inhibitor of STAT3(in HT29 and MDA-MB 231 cells, with IC50 values of 1.82uM and 2.14uM, respectively), induces tumor apoptosis. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

STAT3-IN-1, Inhibitor

Full Product Name

STAT3-IN-1

Product Gene Name

STAT3-IN-1, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

475.53

Solubility

DMSO: 125mg/mL (262.86mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C28H29NO6

SMILES

COc1cc(OC)cc(\C=C\c2ccc(NC(=O)\C=C\c3cc(OC)c(OC)c(OC)c3)cc2)c1

CAS Number

2059952-75-7

Target & IC50

STAT3: ic50 2.14uM (in MDA-MB 231 cells)
STAT3 in HT29 cells: ic50 1.82uM
STAT3 in MDA-MB 231 cells: ic50 2.14uM

Product Categories/Family for STAT3-IN-1, inhibitor

JAK/STAT signaling; STAT; Stem Cells

Product References and Citations for STAT3-IN-1, inhibitor

Li S, et al. Discovery of oral-available resveratrol-caffeic acid based hybrids inhibiting acetylated and phosphorylated STAT3 protein. Eur J Med Chem. 2016 Nov 29;124:1006-1018.

Other Notes

Small volumes of STAT3-IN-1, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for STAT3-IN-1 purchase

MBS5753970 is an inhibitor targeting STAT3-IN-1.