TAT-NR2B9c Inhibitor – TFA

Tat-NR2B9c TFA is a 20-aa peptide, and acts as an inhibitor of postsynaptic density-95 (PSD-95)(EC50 of 6.7nM for PSD-95d2), and possesses neuroprotective efficacy.

Cui H, et al. PDZ protein interactions underlyingnMDA receptor-mediated excitotoxicity and neuroprotection by PSD-95 inhibitors. J Neurosci. 2007 Sep 12;27(37):9901-15.
Cui H, et al. PDZ protein interactions underlyingnMDA receptor-mediated excitotoxicity and neuroprotection by PSD-95 inhibitors. J Neurosci. 2007 Sep 12;27(37):9901-15.
Fan J, et al. P38 MAPK is involved in enhancednMDA receptor-dependent excitotoxicity in YAC transgenic mouse model of Huntington disease. Neurobiol Dis. 2012 Mar;45(3):999-1009.
Fan J, et al. P38 MAPK is involved in enhancednMDA receptor-dependent excitotoxicity in YAC transgenic mouse model of Huntington disease. Neurobiol Dis. 2012 Mar;45(3):999-1009.

Small volumes of Tat-NR2B9c, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5754026 is an inhibitor targeting Tat-NR2B9c. Also known as Tat-NR2B9c TFA.