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4E2RCat Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5754436

MBS5754436 is an inhibitor targeting 4E2RCat. 4E2RCat is an eIF4E-eIF4G interaction inhibitor (IC50: 13.5uM). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
4E2RCat, Inhibitor
Full Product Name
4E2RCat
Product Gene Name
4E2RCat, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
455.93
Solubility
DMSO: 15.5mg/mL (34.00mM) Need ultrasonic and warming
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C22H14ClNO4S2
SMILES
O=C(O)C1=CC(C2=CC=C(/C=C(SC(N3CC4=CC=CC=C4)=S)/C3=O)O2)=CC=C1Cl
CAS Number
432499-63-3
Target & IC50
eIF4E-eIF4G: ic50 13.5uM
In Vitro
4E2RCat inhibits protein synthesis in vivo and it is not a consequence of increased cell death[1].

Structure of 4E2RCat, inhibitor

4E2RCat Inhibitor – Cat# MBS5754436

Product References and Citations for 4E2RCat, inhibitor

Cencic R, et al. Blocking eIF4E-eIF4G interaction as a strategy to impair coronavirus replication. J Virol. 2011 Jul;85(13):6381-9.
Cencic R, et al. Blocking eIF4E-eIF4G interaction as a strategy to impair coronavirus replication. J Virol. 2011 Jul;85(13):6381-9.

Other Notes

Small volumes of 4E2RCat, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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