GW-406381 Inhibitor

GW406381 is a highly selective inhibitor of cyclooxygenase-2 (COX-2). GW406381 also attenuates spontaneous ectopic discharge in the sural nerves of rats following chronic constriction injury.

Zhao FY, et al. GW406381, a novel COX-2 inhibitor, attenuates spontaneous ectopic discharge in sural nerves of rats following chronic constriction injury. Pain. 2007 Mar;128(1-2):78-87.
Zhao FY, et al. GW406381, a novel COX-2 inhibitor, attenuates spontaneous ectopic discharge in sural nerves of rats following chronic constriction injury. Pain. 2007 Mar;128(1-2):78-87.
Boswell DJ, et al. Evaluation of GW406381 for treatment,of osteoarthritis of the knee: two randomized, controlled studies. Medscape J Med. 2008;10(11):259.
Boswell DJ, et al. Evaluation of GW406381 for treatment,of osteoarthritis of the knee: two randomized, controlled studies. Medscape J Med. 2008;10(11):259.

Small volumes of GW-406381, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5754938 is an inhibitor targeting GW-406381.