MCL1-IN-8 Inhibitor

Name: MCL1-IN-8 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5755173
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755173

Mcl1-IN-8 is an Mcl-1-PUMA interface inhibitor (Ki: 0.3uM). In cancer cells, Mcl1-IN-8 shows dual activity on reducing PUMA-dependent apoptosis while deactivating Mcl-1-mediated anti-apoptosis. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Mcl1-IN-8, Inhibitor

Full Product Name

Mcl1-IN-8

Product Gene Name

Mcl1-IN-8, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

393.5

Solubility

DMSO: 50mg/mL (127.06mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C22H23N3O2S

SMILES

O=C1N=C(N2CCN(CCO)CC2)S/C1=C\C3=CC=C(C4=CC=CC=C4)C=C3

CAS Number

678158-55-9

Target & IC50

Mcl-1: ic50 0.3uM (ki)

Product Categories/Family for Mcl1-IN-8, inhibitor

Apoptosis

Product References and Citations for Mcl1-IN-8, inhibitor

Liu J, et al. Targeting the apoptotic Mcl-1-PUMA interface with a dual-acting compound. Oncotarget. 2017 Apr 20;8(33):54236-54242.

Other Notes

Small volumes of Mcl1-IN-8, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Mcl1-IN-8 purchase

MBS5755173 is an inhibitor targeting Mcl1-IN-8.