Human ARNT2 cDNA Clone Expression Plasmid – Cat# MBS1266883

ARNT2 cDNA Clone – Aryl-Hydrocarbon Receptor Nuclear Translocator 2 (Human)

Name: ARNT2 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1266883
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1266883

MBS1266883 is a cDNA clone targeting ARNT2. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ARNT2, cDNA Clone

Full Product Name

ARNT2 cDNA Clone

Product Gene Name

ARNT2 cdna clone

Sequence

atggcaaccc cggcggcggt caaccctccg gaaatggctt cagacatacc tggatctgtg acgttgcccg ttgcccccat ggcggccacc ggacaggtga ggatggcggg ggccatgcct gcccgtggag gaaagcggcg ttccggaatg gacttcgatg atgaagatgg tgaaggcccc agtaaatttt caagagagaa tcatagtgaa atcgaaaggc gcagacggaa caagatgact cagtacatca cggagctctc cgacatggtc cccacatgca gcgcactggc tcggaagcca gacaagctca ccatcctccg catggccgtc tcgcacatga agtccatgag gggtacaggg aacaagtcca ccgatggcgc gtacaagcct tccttcctca cagagcagga actgaagcat ctcatccttg aagcagctga tggatttctg tttgtggtgg ctgctgagac agggcgagtg atttatgtgt ctgactccgt cacccctgtt ctgaaccagc cccagtcaga gtggtttggg agcacactgt atgaacaggt gcatcctgat gacgtggaga agctgagaga gcaactgtgc acctcagaaa actcaatgac aggccggatc ttggacctga agactgggac ggtcaagaaa gaagggcagc agtcatccat gaggatgtgc atgggctcgc ggcggtcttt catctgcagg atgaggtgtg gaaatgctcc tttggaccac cttcctctaa acagaataac caccatgagg aaaaggttca ggaatggcct tggccctgtg aaagaaggag aagcccaata tgctgtggtc cactgtacag gatacatcaa ggcctggcca ccagcaggaa tgaccatacc tgaagaagac gctgatgtgg gacaaggcag taaatattgc ctcgtggcaa ttgggagact ccaggtgacc agctctcctg tatgcatgga catgaatggg atgtcggtgc ccacagagtt cttatcccgg cataactccg atggaatcat cacatttgtg gatccaagat gtatcagtgt gattggctac caaccgcagg atcttctggg aaaggacatt ttggaattct gccaccctga ggatcaaagc catctgcgtg agagcttcca gcaggtggtt aagctgaaag gccaagtcct gtcggtcatg tatcgatttc gcaccaagaa ccgggagtgg atgttgatcc gcaccagcag cttcacattc cagaatccct attctgatga gattgagtac atcatctgca ccaacaccaa cgtcaagcaa cttcagcaac agcaggcaga attggaagtg caccagagag atggattgtc atcgtatgac ttatcccagg tccccgtccc caacctacca gccggtgttc atgaggccgg gaagtccgtg gaaaaggcgg atgcaatctt ctcccaggaa agagatcctc ggtttgctga aatgtttgca ggaattagtg catcggagaa gaagatgatg agctcagcct ctgcagcagg aacccagcag atctactccc aaggaagccc atttccctct ggacactccg ggaaggcctt cagctcttca gtggttcatg tgcctggagt gaatgatatt cagtcctctt cttccacggg ccagaacatg tcccaaatct cccggcagct aaaccagagt caggtggcat ggacagggag tcgtccgccc tttccgggac agcaaatccc atctcagtcc agcaagactc agtcatctcc ctttgggatt ggaacgagcc acacctaccc ggcagacccc tcttcctaca gccccctctc cagcccagct acctcctcgc caagtgggaa tgcctactcc agtcttgcca acaggactcc agggttcgct gaaagtggac aaagtagcgg gcagttccaa gggcggccct cggaagtctg gtcgcagtgg caaagccagc accatggcca gcagagcggt gagcagcact cccaccagca gcccggtcag actgaagtgt tccaggacat gctgcccatg ccaggagatc cagggaatga atggtggtct ccccactccc ggcagcactt taggcagccc ataagctatg cgagaatgtg a

Molecular Weight

77,612 Da

OMIM

606036

Vector

pENTR223.1

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ARNT2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ARNT2. It may not necessarily be applicable to this product.

NCBI GI #

23271920

NCBI GeneID

9915

NCBI Accession #

BC036099

UniProt Secondary Accession #

O15024; Q8IYC2; B4DIS7

UniProt Related Accession #

Q9HBZ2

NCBI Official Full Name

Homo sapiens aryl-hydrocarbon receptor nuclear translocator 2, mRNA

NCBI Official Synonym Full Names

aryl hydrocarbon receptor nuclear translocator 2

NCBI Official Symbol

ARNT2

NCBI Official Synonym Symbols

WEDAS; bHLHe1

UniProt Protein Name

Aryl hydrocarbon receptor nuclear translocator 2

UniProt Synonym Protein Names

Class E basic helix-loop-helix protein 1; bHLHe1

Protein Family

Aryl hydrocarbon receptor nuclear translocator

UniProt Gene Name

ARNT2

UniProt Synonym Gene Names

BHLHE1; KIAA0307; ARNT protein 2; bHLHe1

UniProt Entry Name

ARNT2_HUMAN

NCBI Protein Information

aryl hydrocarbon receptor nuclear translocator 2

NCBI Summary for ARNT2

This gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively. [provided by RefSeq, Dec 2013]

UniProt Comments for ARNT2

ARNT2: Specifically recognizes the xenobiotic response element (XRE). 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis; DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 15q24

Cellular Component: nucleus

Molecular Function: aryl hydrocarbon receptor binding; protein heterodimerization activity; transcription factor activity

Biological Process: brain development; central nervous system development; in utero embryonic development; positive regulation of transcription, DNA-dependent; regulation of transcription, DNA-dependent; response to hypoxia

Disease: Webb-dattani Syndrome

Research Articles on ARNT2

1. Attenuated ARNT2 expression in HCC827 cells greatly promoted tumor growth.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with ARNT2 cdna clone

Products by Pathway	Pathway Diagram
Pathways In Cancer antibodies	Pathways In Cancer Diagram
Renal Cell Carcinoma Pathway antibodies	Renal Cell Carcinoma Pathway Diagram
Renal Cell Carcinoma Pathway antibodies	Renal Cell Carcinoma Pathway Diagram
Transcriptional Misregulation In Cancer Pathway antibodies	Transcriptional Misregulation In Cancer Pathway Diagram
Transcriptional Misregulation In Cancer Pathway antibodies	Transcriptional Misregulation In Cancer Pathway Diagram

Diseases associated with ARNT2 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>10 publications with ARNT2 and Neoplasms
Drug Toxicity Antibodies	>10 publications with ARNT2 and Drug Toxicity
Congenital Abnormalities Antibodies	>5 publications with ARNT2 and Congenital Abnormalities
Liver Neoplasms Antibodies	>4 publications with ARNT2 and Liver Neoplasms
Liver Diseases Antibodies	>4 publications with ARNT2 and Liver Diseases
Carcinoma, Hepatocellular Antibodies	>3 publications with ARNT2 and Carcinoma, Hepatocellular
Breast Neoplasms Antibodies	>3 publications with ARNT2 and Breast Neoplasms
Nervous System Diseases Antibodies	>3 publications with ARNT2 and Nervous System Diseases
Hypertrophy Antibodies	>2 publications with ARNT2 and Hypertrophy
Urogenital Abnormalities Antibodies	>2 publications with ARNT2 and Urogenital Abnormalities

Organs/Tissues associated with ARNT2 cdna clone

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>34 publications with ARNT2 and Brain
Liver Antibodies	>20 publications with ARNT2 and Liver
Kidney Antibodies	>15 publications with ARNT2 and Kidney
Heart Antibodies	>9 publications with ARNT2 and Heart
Embryonic Tissue Antibodies	>9 publications with ARNT2 and Embryonic Tissue
Nerve Antibodies	>8 publications with ARNT2 and Nerve
Vascular Antibodies	>7 publications with ARNT2 and Vascular
Muscle Antibodies	>4 publications with ARNT2 and Muscle
Uterus Antibodies	>3 publications with ARNT2 and Uterus
Lung Antibodies	>3 publications with ARNT2 and Lung