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Mirodenafil Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755190

Mirodenafil is a PDE-5 inhibitor developed for the treatment,of erectile dysfunction. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Mirodenafil, Inhibitor
Full Product Name
Mirodenafil
Product Synonym Names
SK3530
Form/Format
Solid. Powder
Purity/Purification
99.85%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
531.67
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C26H37N5O5S
SMILES
CCCOc1ccc(cc1-c1nc2c(CCC)cn(CC)c2c(=O)[nH]1)S(=O)(=O)N1CCN(CCO)CC1
CAS Number
862189-95-5
Target & IC50
Others
In Vitro
The pharmacoki-netics of mirodenafil were not significantly altered by this concurrent administration. Mirodenafil (50 or 100 mg), obviously improved erectile function and was well tolerated in a representative population of Korean men with broad-spectrum ED of various etiologies and severities [1]. Mirodenafil administered with alcohol had a tolerability profile comparable to that of mirodenafil alone [2]. The concurrent administration of mirodenafil with alcohol was not associated with clinically significant hemodynamic changes in these healthy male volunteers in Korea. The coadministration of ketoconazole and rifampicin resulted in significant changes in systemic exposure to mirodenafil, in these healthy Korean male volunteers [3].

Product Categories/Family for Mirodenafil, inhibitor

Product References and Citations for Mirodenafil, inhibitor

Paick, J.S., et al., Efficacy and safety of mirodenafil, a new oral phosphodiesterase type 5 inhibitor, for treatment,of erectile dysfunction. J Sex Med, 2008. 5(11): p. 2672-80.
Paick, J.S., et al., Efficacy and safety of mirodenafil, a new oral phosphodiesterase type 5 inhibitor, for treatment,of erectile dysfunction. J Sex Med, 2008. 5(11): p. 2672-80.
Kim, B.H., et al., Influence of alcohol on the hemodynamic effects and pharmacokinetic properties of mirodenafil: a single-dose, randomized-sequence, open-label, crossover study in healthy male volunteers in Korea. Clin Ther, 2009. 31(6): p. 1234-43.
Kim, B.H., et al., Influence of alcohol on the hemodynamic effects and pharmacokinetic properties of mirodenafil: a single-dose, randomized-sequence, open-label, crossover study in healthy male volunteers in Korea. Clin Ther, 2009. 31(6): p. 1234-43.
Shin, K.H., et al., The effects of ketoconazole and rifampicin on the pharmacokinetics of mirodenafil in healthy Korean male volunteers: an open-label, one-sequence, three-period, three-treatment,crossover study. Clin Ther, 2009. 31(12): p. 3009-20.
Shin, K.H., et al., The effects of ketoconazole and rifampicin on the pharmacokinetics of mirodenafil in healthy Korean male volunteers: an open-label, one-sequence, three-period, three-treatment,crossover study. Clin Ther, 2009. 31(12): p. 3009-20.

Other Notes

Small volumes of Mirodenafil, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Mirodenafil purchase

MBS5755190 is an inhibitor targeting Mirodenafil.
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