Praliciguat Inhibitor

Name: Praliciguat Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5755405
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755405

Praliciguat stimulates sGC in HEK-293 cells (EC50: 197nM). Praliciguat is an effective and orally active soluble guanylate cyclase stimulator. It also enhances NO signaling and acts as a vasodilator. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Praliciguat, Inhibitor

Full Product Name

Praliciguat

Product Synonym Names

IW-1973

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

534.36

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C21H14F8N6O2

SMILES

FC1=C(C=CC=C1)CN2C(C3=NOC=C3)=CC(C4=NC=C(F)C(NCC(C(F)(F)F)(O)C(F)(F)F)=N4)=N2

CAS Number

1628730-49-3

Target & IC50

sGC: ic50 197nM (EC50)

Product Categories/Family for Praliciguat, inhibitor

Metabolism; Others

Product References and Citations for Praliciguat, inhibitor

Daniel P Zimmer, et al. Abstract 16938: IW-1973 is a Potent Soluble Guanylate Cyclase Stimulator in vitro and in vivo With Extensive Tissue Distribution.
Daniel P Zimmer, et al. Abstract 16938: IW-1973 is a Potent Soluble Guanylate Cyclase Stimulator in vitro and in vivo With Extensive Tissue Distribution.

Other Notes

Small volumes of Praliciguat, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Praliciguat purchase

MBS5755405 is an inhibitor targeting Praliciguat.