SR-31747 Inhibitor

Name: SR-31747 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5755551
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755551

SR-31747 blocks cell proliferation by inhibiting sterol isomerase. SR-31747 is a sigma ligand. It has immunosuppressive and anti-inflammatory properties. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SR-31747, Inhibitor

Full Product Name

SR-31747

Product Gene Name

SR-31747, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

396.44

Solubility

DMSO: 15.62mg/mL (39.40mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C23H35Cl2N

SMILES

CCN(C/C=C\C1=CC=C(C2CCCCC2)C(Cl)=C1)C3CCCCC3.Cl

CAS Number

132173-07-0

Target & IC50

Sigma ligand

In Vitro

SR-31747 (10nM) blocks the proliferation of lymphocytes at a concentration. SR-31747 arrests proliferation in yeast cells in a dose-dependent manner. SR-31747 is capable of inhibiting T-cell proliferation when added as late as 24 hours after activation [2].

Product References and Citations for SR-31747, inhibitor

Derocq JM, et al. In vivo inhibition of endotoxin-induced pro-inflammatory cytokines production by the sigma ligand SR 31747. J Pharmacol Exp Ther. 1995 Jan;272(1):224-30.
Derocq JM, et al. In vivo inhibition of endotoxin-induced pro-inflammatory cytokines production by the sigma ligand SR 31747. J Pharmacol Exp Ther. 1995 Jan;272(1):224-30.
Silve S, et al. The immunosuppressant SR 31747 blocks cell proliferation by inhibiting a steroid isomerase in Saccharomyces cerevisiae. Mol Cell Biol. 1996 Jun;16(6):2719-27.
Silve S, et al. The immunosuppressant SR 31747 blocks cell proliferation by inhibiting a steroid isomerase in Saccharomyces cerevisiae. Mol Cell Biol. 1996 Jun;16(6):2719-27.

Other Notes

Small volumes of SR-31747, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

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MBS5755551 is an inhibitor targeting SR-31747.

SR-31747 Inhibitor

Product Overview

Structure of SR-31747, inhibitor

Related Product Information for SR-31747, inhibitor

Product References and Citations for SR-31747, inhibitor

Other Notes

Searchable Terms for SR-31747 purchase