Tauroursodeoxycholate dihydrate Inhibitor

Name: Tauroursodeoxycholate dihydrate Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5755590
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755590

Tauroursodeoxycholate dihydrate is an endoplasmic reticulum stress inhibitor. Tauroursodeoxycholate also inhibits ERK. Tauroursodeoxycholate significantly decreases the expression of apoptosis molecules, such as caspase-3 and caspase-12. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Tauroursodeoxycholate dihydrate, Inhibitor

Full Product Name

Tauroursodeoxycholate dihydrate

Product Synonym Names

TUDCA dihydrate; UR 906 dihydrate; Taurolite dihydrate

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

535.73

Solubility

DMSO: 83.33mg/mL (155.54mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C26H49NO8S

SMILES

C[C@H](CCC(NCCS(=O)(O)=O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])[C@@H](O)C[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC[C@]12C.O.O

CAS Number

117609-50-4

Target & IC50

ERK
Caspase-3
Caspase-12

Product Categories/Family for Tauroursodeoxycholate dihydrate, inhibitor

MAPK; ERK; Apoptosis; Proteases/Proteasome

Product References and Citations for Tauroursodeoxycholate dihydrate, inhibitor

Kim SY, et al. Tauroursodeoxycholate (TUDCA) inhibits neointimal hyperplasia by suppression of ERK viaPKCalpha-mediated MKP-1 induction. Cardiovasc Res. 2011 Nov 1;92(2):307-16.
Kim SY, et al. Tauroursodeoxycholate (TUDCA) inhibits neointimal hyperplasia by suppression of ERK viaPKCalpha-mediated MKP-1 induction. Cardiovasc Res. 2011 Nov 1;92(2):307-16.
Qin Y, et al. Tauroursodeoxycholic Acid Attenuates Angiotensin II Induced Abdominal Aortic Aneurysm Formation in Apolipoprotein E-deficient Mice by Inhibiting Endoplasmic Reticulum Stress. Eur J Vasc Endovasc Surg. 2017 Mar;53(3):337-345.
Qin Y, et al. Tauroursodeoxycholic Acid Attenuates Angiotensin II Induced Abdominal Aortic Aneurysm Formation in Apolipoprotein E-deficient Mice by Inhibiting Endoplasmic Reticulum Stress. Eur J Vasc Endovasc Surg. 2017 Mar;53(3):337-345.

Other Notes

Small volumes of Tauroursodeoxycholate dihydrate, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Tauroursodeoxycholate dihydrate purchase

MBS5755590 is an inhibitor targeting Tauroursodeoxycholate dihydrate.