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Zardaverine Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755728

Zardaverine is a newly developed dual-selective PDE3/4 inhibitor (IC50: 0.5uM and 0.8 uM respectively). More details

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Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Zardaverine, Inhibitor
Full Product Name
Zardaverine
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
268.22
Solubility
DMSO: 100mg/mL (372.83mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C12H10F2N2O3
SMILES
O=C1C=CC(C2=CC=C(OC(F)F)C(OC)=C2)=NN1
CAS Number
101975-10-4
Target & IC50
Others

Structure of Zardaverine, inhibitor

Zardaverine Inhibitor – Cat# MBS5755728

Product References and Citations for Zardaverine, inhibitor

R. T. Schermuly, H. Leuchte, H. A. Ghofrani, et al. Zardaverine and aerosolised iloprost in a model of acute respiratoryfailure. ERJ, 2003,22 (2): 342-347.
D. Ukena, K. Rentz, C. Reiber, et al. Effects of the mixed phosphodiesterase III/IV inhibitor, zardaverine, on airway function in patients with chronic airflow obstruction. Respiratory Medicine.1995, 89 (6) : 441-444.
Schade FU, Schudt C. The specific type III and IV phosphodiesterase inhibitor zardaverine suppresses formation of tumor necrosis factor by macrophages. European Journal of Pharmacology.1993, 230(1):9-14.

Other Notes

Small volumes of Zardaverine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Zardaverine purchase

MBS5755728 is an inhibitor targeting Zardaverine.
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