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2S,4R-Sacubitril Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5755919

2S,4R-Sacubitril is the impurity of Sacubitril. Sacubitril is used in combination with valsartan for the treatment,of patients with heart failure. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
2S,4R-Sacubitril, Inhibitor
Full Product Name
2S,4R-Sacubitril
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
425.52
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C25H31NO5
SMILES
[H]N(C(CC(C)C(O)=O)=O)[C@H](CC(C=C1)=CC=C1C2=CC=CC=C2)C[C@@H](C)C(OCC)=O
Target & IC50
Others

Structure of 2S,4R-Sacubitril, inhibitor

2S,4R-Sacubitril Inhibitor – Cat# MBS5755919

Product References and Citations for 2S,4R-Sacubitril, inhibitor

Shi J, et al. Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation. Drug Metab Dispos. 2016 Apr;44(4):554-9.
Shi J, et al. Sacubitril Is Selectively Activated by Carboxylesterase 1 (CES1) in the Liver and the Activation Is Affected by CES1 Genetic Variation. Drug Metab Dispos. 2016 Apr;44(4):554-9.

Other Notes

Small volumes of 2S,4R-Sacubitril, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

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MBS5755919 is an inhibitor targeting 2S,4R-Sacubitril.
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