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Lithospermate B Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5756547

Lithospermate B is a natural product activates eNOS and ameliorates endothelial dysfunction in diabetes by enhancing vasodilation in addition to reducing oxidative stress, it can protecte cardiomyocytes from ischemic injury through specific inhibition of… More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Lithospermate B, Inhibitor
Full Product Name
Lithospermate B
Product Synonym Names
Monomethyl lithospermate B
Form/Format
Solid. Powder
Purity/Purification
99.87%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
740.90
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C36H28MgO16
SMILES
[Mg++].Oc1ccc(\C=C\C(=O)OC(Cc2ccc(O)c(O)c2)C([O-])=O)c2C(C(Oc12)c1ccc(O)c(O)c1)C(=O)OC(Cc1ccc(O)c(O)c1)C([O-])=O
CAS Number
122021-74-3
Target & IC50
Others
In Vitro
magnesium lithospermate B (MLB), a bioactive ingredient extracted from Salvia miltiorrhiza, exerts neuroprotective effects in several central nervous system insults. Administration of MLB significantly attenuated brain edema and neurological deficits after SAH[1].

Product References and Citations for Lithospermate B, inhibitor

1.Yucong P, Pingyou H, Linfeng F, et al. Neuroprotective Effects of Magnesium Lithospermate B against Subarachnoid Hemorrhage in Rats[J]. The American Journal of Chinese Medicine, 2018, 46:1-17.
Yucong P, Pingyou H, Linfeng F, et al. Neuroprotective Effects of Magnesium Lithospermate B against Subarachnoid Hemorrhage in Rats[J]. The American Journal of Chinese Medicine, 2018, 46:1-17.
Zhang Z, Zichen W, Wei R, et al. Magnesium lithospermate B promotes proliferation and differentiation of neural stem cells in vitro and enhances neurogenesis in vivo[J]. Tissue & Cell, 2018, 53:8-14.
Zhang Z, Zichen W, Wei R, et al. Magnesium lithospermate B promotes proliferation and differentiation of neural stem cells in vitro and enhances neurogenesis in vivo[J]. Tissue & Cell, 2018, 53:8-14.

Other Notes

Small volumes of Lithospermate B, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Lithospermate B purchase

MBS5756547 is an inhibitor targeting Lithospermate B.
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