Sophoraflavanone G Inhibitor

Name: Sophoraflavanone G Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5758254
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758254

Norkurarinone is iaolated from Sophora flavescens and shows anti-tumor and anti-inflammatory properties, induces MDA-MB-231 and HL-60 cells apoptosis through suppression of MAPK-related pathways. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Sophoraflavanone G, Inhibitor

Full Product Name

Sophoraflavanone G

Product Synonym Names

Kushenol F; Vexibinol

Form/Format

Solid. Powder

Purity/Purification

99.20%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

424.49

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C25H28O6

SMILES

CC(C)=CC[C@H](Cc(c(O[C@@H](CC1=O)c(ccc(O)c2)c2O)c1c(O)c1)c1O)C(C)=C

CAS Number

97938-30-2

Target & IC50

Apoptosis inducer
MDA-MB-231 cell: ic50

Cell Research

explore its molecular mechanism in human leukemia HL-60 cells. HL-60 cells were treated with various concentrations of SG (3-30 [Formula: see text]M). The viability of the HL-60 cells was assessed using the MTT method, and the nuclear condensation indicative of apoptosis was observed by DAPI fluorescence staining. In addition, apoptotic signal proteins were examined using Western blotting.

Product Categories/Family for Sophoraflavanone G, inhibitor

Apoptosis; Apoptosis inducer

Product References and Citations for Sophoraflavanone G, inhibitor

Li ZY, et al. Sophoraflavanone G Induces Apoptosis in Human Leukemia Cells and Blocks MAPK Activation. Am J Chin Med. 2016;44(1):165-76.
Li ZY, et al. Sophoraflavanone G Induces Apoptosis in Human Leukemia Cells and Blocks MAPK Activation. Am J Chin Med. 2016;44(1):165-76.
Huang WC, et al. Sophoraflavanone G from Sophora flavescens induces apoptosis in triple-negative breast cancer cells.Phytomedicine. 2019 Aug;61:152852.
Huang WC, et al. Sophoraflavanone G from Sophora flavescens induces apoptosis in triple-negative breast cancer cells.Phytomedicine. 2019 Aug;61:152852.

Other Notes

Small volumes of Sophoraflavanone G, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Sophoraflavanone G purchase

MBS5758254 is an inhibitor targeting Sophoraflavanone G.