BD1063 Inhibitor

MBS5758382 is an inhibitor targeting BD1063. BD1063 is a potent and selective sigma 1(sigma1) receptor antagonist(Ki = 9nM).

Sabino V, Cottone P, Zhao Y, et al. The sigma-Receptor Antagonist BD-1063 Decreases Ethanol Intake and Reinforcement in Animal Models of Excessive Drinking[J]. Neuropsychopharmacology, 2009, 34(6):1482-1493.
Sabino V, Cottone P, Zhao Y, et al. The sigma-Receptor Antagonist BD-1063 Decreases Ethanol Intake and Reinforcement in Animal Models of Excessive Drinking[J]. Neuropsychopharmacology, 2009, 34(6):1482-1493.
Nieto F R, Cruz Miguel Cendan, Cristina Sanchez-Fernandez, et al. Role of Sigma-1 Receptors in Paclitaxel-Induced Neuropathic Pain in Mice[J]. The journal of pain: official journal of the American Pain Society, 2012, 13(11):1107-1121.
Nieto F R, Cruz Miguel Cendan, Cristina Sanchez-Fernandez, et al. Role of Sigma-1 Receptors in Paclitaxel-Induced Neuropathic Pain in Mice[J]. The journal of pain: official journal of the American Pain Society, 2012, 13(11):1107-1121.

Small volumes of BD1063, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.