Phenprocoumon Inhibitor

MBS5758528 is an inhibitor targeting Phenprocoumon. Phenprocoumon is an antagonist of vitamin K(IC50:1uM).

Martin, Muller, Fabian, et al. Characteristics, treatment, and outcome of bleeding after tooth extraction in patients on DOAC and phenprocoumon compared to non-anticoagulated patients-a retrospective study of emergency department consultations.[J]. Clinical oral investigations, 2018.
Martin, Muller, Fabian, et al. Characteristics, treatment, and outcome of bleeding after tooth extraction in patients on DOAC and phenprocoumon compared to non-anticoagulated patients-a retrospective study of emergency department consultations.[J]. Clinical oral investigations, 2018.
Trenk D, Beermann D, Oesch F, et al. Age-dependent differences in the effect of phenprocoumon on the vitamin K1-epoxide cycle in rats[J]. Journal of Pharmacy and Pharmacology, 1981, 32(12):828-832.
Trenk D, Beermann D, Oesch F, et al. Age-dependent differences in the effect of phenprocoumon on the vitamin K1-epoxide cycle in rats[J]. Journal of Pharmacy and Pharmacology, 1981, 32(12):828-832.

Small volumes of Phenprocoumon, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.