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C25-140 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5758751

MBS5758751 is an inhibitor targeting C25-140. C25-140 is a small-molecule inhibitor of TRAF6-Ubc13. More details

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Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
C25-140, Inhibitor
Full Product Name
C25-140
Product Gene Name
C25-140, inhibitor
Form/Format
Solid. Powder
Purity/Purification
100.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
457.60
Solubility
DMSO: 62.5mg/mL (136.59mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C26H31N7O
SMILES
Cc1nn(-c2ccc3nnc(C)n3n2)c(C)c1CCC(=O)N1CCC(Cc2ccccc2)CC1
CAS Number
1358099-18-9
Target & IC50
NF-kappaB
TRAF6-Ubc13
Cell Research
Cell Line: TRAF6WT. Concentration: 10uM, 20uM, 30uM. Incubation Time: 2 hours

Product Categories/Family for C25-140, inhibitor

NF-kappab; NF-kappaB; Others

Structure of C25-140, inhibitor

C25-140 Inhibitor – Cat# MBS5758751

Product References and Citations for C25-140, inhibitor

Kerstin B J, Maria P G, Kenji S, et al. Targeting TRAF6 E3 ligase activity with a small molecule inhibitor combats autoimmunity[J]. Journal of Biological Chemistry, 2018:jbc.RA118.002649-.

Other Notes

Small volumes of C25-140, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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