BMS-1001 Inhibitor

Name: BMS-1001 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5759264
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759264

BMS-1001 is a potent inhibitor of PD-1/PD-L1 interaction(IC50 : 2.25nM, in a homogenous time-resolved fluorescence binding assay). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

BMS-1001, Inhibitor

Full Product Name

BMS-1001

Product Gene Name

BMS-1001, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

594.70

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C35H34N2O7

SMILES

CC1=CC(CN[C@H](CO)C(O)=O)=C(OCC2=CC(=CC=C2)C#N)C=C1OCC1=C(C)C(=CC=C1)C1=CC2=C(OCCO2)C=C1

CAS Number

2113650-03-4

Target & IC50

PD-1/PD-L1

Product Categories/Family for BMS-1001, inhibitor

Apoptosis; PD-1/PD-L1; Cell Cycle/Checkpoint; Immunology/Inflammation

Product References and Citations for BMS-1001, inhibitor

Skalniak L, Zak K M, Guzik K, et al. Small-molecule inhibitors of PD-1/PD-L1 immune checkpoint alleviate the PD-L1-induced exhaustion of T-cells[J]. Oncotarget, 2017, 8(42).

Other Notes

Small volumes of BMS-1001, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BMS-1001 purchase

MBS5759264 is an inhibitor targeting BMS-1001.