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BC-1382 Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759350

BC-1382 is a potent ubiquitin E3 ligase HECTD2 inhibitor that specificly disrupts the HECTD2/PIAS1 interaction(IC50 of 5nM). More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
BC-1382, Inhibitor
Full Product Name
BC-1382
Product Gene Name
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
459.558
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C23H29N3O5S
SMILES
COc1ccccc1CNC(=O)[C@H](C)NC(=O)C1CCN(CC1)S(=O)(=O)c1ccccc1
CAS Number
1013753-99-5
Target & IC50
ubiquitin E3 ligase HECTD2
In Vitro
BC-1382, that targeted HECTD2 and attenuated lipopolysaccharide (LPS)- and Pseudomonas aeruginosa-induced lung inflammation.

Structure of BC-1382, inhibitor

BC-1382 Inhibitor – Cat# MBS5759350

Product References and Citations for BC-1382, inhibitor

Coon T A, Mckelvey A C, Lear T, et al. The proinflammatory role of HECTD2 in innate immunity and experimental lung injury[J]. ence Translational Medicine, 2015, 7(295):295ra109.

Other Notes

Small volumes of BC-1382, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BC-1382 purchase

MBS5759350 is an inhibitor targeting BC-1382.
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