PLX-4032 Inhibitor

Name: PLX-4032 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5759437
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759437

PLX-4032 is a small-molecule B-Raf inhibitor for the potential treatment,of malignant melanoma. More details

Please Inquire

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Plx-4032, Inhibitor

Full Product Name

Plx-4032

Product Gene Name

Plx-4032, inhibitor

Product Synonym Names

Vemurafenib

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

489.92

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C23H18ClF2N3O3S

SMILES

CCCS(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(cc23)-c2ccc(Cl)cc2)c1F

CAS Number

1029872-54-5

Target & IC50

B-Raf

Product Categories/Family for Plx-4032, inhibitor

MAPK; Raf

Product References and Citations for Plx-4032, inhibitor

Smalley K S M. PLX-4032, a small-molecule B-Raf inhibitor for the potential treatment,of malignant melanoma.[J]. Current Opinion in Investigational Drugs, 2010, 11(6):699-706.
Smalley K S M. PLX-4032, a small-molecule B-Raf inhibitor for the potential treatment,of malignant melanoma.[J]. Current Opinion in Investigational Drugs, 2010, 11(6):699-706.
Chapman, Paul, B, et al. Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation.[J]. New England Journal of Medicine, 2011.
Chapman, Paul, B, et al. Improved Survival with Vemurafenib in Melanoma with BRAF V600E Mutation.[J]. New England Journal of Medicine, 2011.

Other Notes

Small volumes of Plx-4032, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Plx-4032 purchase

MBS5759437 is an inhibitor targeting Plx-4032.