Sulforaphene Inhibitor

Sulforaphene may be a potential anti- triple negative breast cancer natural compound and its /antiproliferation effects may be mediated by tumor suppressor Egr1; it has chemotherapeutic potential, it promotes Bax/Bcl2, MAPK-dependent human gastric cancer AGS cells apoptosis and inhibits migration via EGFR, p-ERK1/2 down-regulation; it enhances radiosensitivity of hepatocellular carcinoma through suppression of the NF-kappaB pathway. Sulforaphene has anti-proliferative and antibacterial properties. Sulforaphene also has herbicidal activity, the ED50 of it against velvetleaf seedlings was approximately 2x10(-4) M.

Herbicidal activity of sulforaphene from stock (Matthiola incana). J Chem Ecol. 1993 Oct;19(10):2279-84.
Sulforaphene inhibits triple negative breast cancer through activating tumor suppressor Egr1. Breast Cancer Res Treat. 2016 Jul;158(2):277-86.
Characterization of Anti-proliferative and Antibacterial Properties of Sulforaphene Obtained from Radish Seeds, Ashs Conference. 2013.

Small volumes of Sulforaphene, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS5759687 is an inhibitor targeting Sulforaphene.