2-Amino-3-carboxy-1,4-naphthoquinone Inhibitor

Name: 2-Amino-3-carboxy-1,4-naphthoquinone Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5759957
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5759957

2-Amino-3-carboxy-1,4-naphthoquinone is a novel growth stimulator for bifidobacteria, it affects the end-product profile of bifidobacteria through the mediated oxidation of NAD(P)H. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

2-Amino-3-carboxy-1,4-naphthoquinone, Inhibitor

Full Product Name

2-Amino-3-carboxy-1,4-naphthoquinone

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

217.18

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C11H7NO4

SMILES

NC(C(c1c2cccc1)=O)=C(C(O)=O)C2=O

CAS Number

173043-38-4

Target & IC50

NADPH-oxidase

In Vitro

Continuous monitoring of ACNQ, O(2) and H(2)O(2) by several amperometric techniques has revealed that ACNQ works as a good electron acceptor of NAD(P)H diaphorase and that the reduced form of ACNQ is easily autoxidized and also acts as a better electron donor of NAD(P)H peroxidase than NAD(P)hours. The generation of H(2)O(2) by B. longum under aerobic conditions is effectively suppressed in the presence of ACNQ. These ACNQ-mediated reactions would play roles as NAD(P)(+)-regeneration processes. The accumulation of ACNQ in the cytosol has been also suggested. These characteristics of ACNQ seem to be responsible for the growth stimulation of bifidobacteria.

Product Categories/Family for 2-Amino-3-carboxy-1,4-naphthoquinone, inhibitor

Immunology/Inflammation; NADPH-oxidase

Product References and Citations for 2-Amino-3-carboxy-1,4-naphthoquinone, inhibitor

Role of 2-amino-3-carboxy-1,4-naphthoquinone, a strong growth stimulator for bifidobacteria, as an electron transfer mediator for NAD(P)(+) regeneration in Bifidobacterium longum. Biochim Biophys Acta. 1999 Aug 5;1428(2-3):241-50.

Other Notes

Small volumes of 2-Amino-3-carboxy-1,4-naphthoquinone, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for 2-Amino-3-carboxy-1,4-naphthoquinone purchase

MBS5759957 is an inhibitor targeting 2-Amino-3-carboxy-1,4-naphthoquinone.