Asimilobine Inhibitor

Name: Asimilobine Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5760152
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5760152

(-)-Asimilobine shows antioxidative, anti-acetylcholinesterase (AChE), anti-alpha+/--glucosidase, anti-leishmanial and anti-fungal activities; it displays weak inhibition against Streptococcus mutans ( 25175), with a minimum inhibition concentration (MIC) of… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Asimilobine, Inhibitor

Full Product Name

Asimilobine

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

267.32

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C17H17NO2

SMILES

COc(c(O)cc1c2[C@@H](C3)NCC1)c2-c1c3cccc1

CAS Number

6871-21-2

Target & IC50

Antifection
AChR

In Vitro

This study was carried out to evaluate the antibacterial potential from aerial parts of plant, called 'Annona senegalensis' and its constituents. Bioassay guided fractionation led to the isolation of four metabolites, (+)-catechin (1), (-)-anonaine (2), (-)-Asimilobine (3) and (+)-nornantenine (4). This is the first report on the isolation of compounds 1, 3 and 4 from this plant. Compounds 2 and 4 showed good activity, whereas 1 and 3 displayed weak inhibition against Streptococcus mutans ( 25175). The results showed that compound 2 and 3 showed significant activity with a minimum inhibition concentration (MIC) of 0.12 and 0.25mg/mL, respectively[1]

Product Categories/Family for Asimilobine, inhibitor

Microbiology/Virology; Antifection; Neuroscience

Product References and Citations for Asimilobine, inhibitor

Alkaloids from aerial parts of Annona senegalensis against Streptococcus mutans.Nat Prod Res. 2017 Aug;31(16):1944-1947.
Alkaloids from aerial parts of Annona senegalensis against Streptococcus mutans.Nat Prod Res. 2017 Aug;31(16):1944-1947.
Antioxidant and anticancer aporphine alkaloids from the leaves of Nelumbo nucifera Gaertn. cv. Rosa-plena.Molecules. 2014 Nov 3;19(11):17829-38.
Anti-acetylcholinesterase, anti-alpha+/--glucosidase, anti-leishmanial and anti-fungal activities of chemical constituents of Beilschmiedia species.Fitoterapia. 2012 Mar;83(2):298-302.

Other Notes

Small volumes of Asimilobine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Asimilobine purchase

MBS5760152 is an inhibitor targeting Asimilobine.