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Isoscoparin Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5760530

Isoscoparin has antioxidant, and anti-adipogenic effects, it may be a potential therapeutic agent for the prevention and treatment,of obesity. Isoscoparin can significantly inhibit the production of both NO and TNF-alpha+/- at a concentration of 2.0uM. More details

Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Isoscoparin, Inhibitor
Full Product Name
Isoscoparin
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
462.4
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C22H22O11
SMILES
COc(cc(cc1)C(Oc2cc(O)c([C@@H]([C@@H]([C@H]3O)O)O[C@H](CO)[C@H]3O)c(O)c22)=CC2=O)c1O
CAS Number
20013-23-4
Target & IC50
Fatty Acid Synthase
NO Synthase
TNF-alpha
In Vitro
Herein, we analysed flavonoids in a yellow grain rice mutant using UHPLC-DAD-ESI-Q-TOF-MS, and identified 19 flavonoids by comparing retention times and accurate mass measurements. Among them, six flavonoids, isoorientin, isoorientin 2"-O-glucoside, vitexin 2"-O-glucoside, isovitexin, Isoscoparin 2"-O-glucoside and Isoscoparin, were isolated and fully identified from the yellow grain rice mutant, and the levels were significantly higher than wild-type, with isoorientin particularly abundant in mutant embryo. Significant differences in total phenolic compounds and antioxidant activity were observed in mutant rice by DPPH, FRAP and TEAC assays[1]

Product References and Citations for Isoscoparin, inhibitor

Identification and quantification of flavonoids in yellow grain mutant of rice (Oryza sativa L.).Food Chem. 2018 Feb 15;241:154-162.
Identification and quantification of flavonoids in yellow grain mutant of rice (Oryza sativa L.).Food Chem. 2018 Feb 15;241:154-162.
A new phenolic component from Triticum aestivum sprouts and its effects on LPS-stimulated production of nitric oxide and TNF-alpha+/- in RAW 264.7 cells.Phytother Res. 2014 Jul;28(7):1064-70.

Other Notes

Small volumes of Isoscoparin, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Isoscoparin purchase

MBS5760530 is an inhibitor targeting Isoscoparin.
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