Rhaponticin 6''-O-gallate Inhibitor

Name: Rhaponticin 6''-O-gallate Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5760865
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5760865

Rhaponticin 6''-O-gallate showed inhibitory activity of NO production in lipopolysaccharide-activated macrophages, (IC50 = 11-69microM). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Rhaponticin 6''-O-gallate, Inhibitor

Full Product Name

Rhaponticin 6''-O-gallate

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

572.51

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C28H28O13

SMILES

COc1ccc(\C=C\c2cc(O)cc(O[C@@H]3O[C@H](COC(=O)c4cc(O)c(O)c(O)c4)[C@@H](O)[C@H](O)[C@H]3O)c2)cc1O

CAS Number

94356-23-7

Target & IC50

NO: ic50 11-69microM
NO Synthase

In Vitro

Two new anthraquinone glucosides [chrysophanol 8-O-beta-D-(6'-galloyl)-glucopyranoside, aloe-emodin 1-O-beta-D-glucopyranoside] together with various known stilbenes and their glucosides, anthraquinone glucosides, and a naphthalene glucoside were isolated from the rhizome of Rheum undulatum L. Three stilbenes (rhapontigenin, piceatannol, resveratrol), a naphthalene glucoside (torachrysone 8-O-beta-D-glucopyranoside), and two stilbene glucoside gallates (rhaponticin 2''-O-gallate, Rhaponticin 6''-O-gallate) showed inhibitory activity of NO production in lipopolysaccharide-activated macrophages, (IC50 = 11-69microM).

Product Categories/Family for Rhaponticin 6''-O-gallate, inhibitor

Immunology/Inflammation

Product References and Citations for Rhaponticin 6''-O-gallate, inhibitor

Effects of stilbene constituents from rhubarb on nitric oxide production in lipopolysaccharide-activated macrophages. Bioorg Med Chem Lett. 2000 Feb 21;10(4):323-7.

Other Notes

Small volumes of Rhaponticin 6''-O-gallate, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Rhaponticin 6''-O-gallate purchase

MBS5760865 is an inhibitor targeting Rhaponticin 6''-O-gallate.