Roemerine Inhibitor

Name: Roemerine Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5760872
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5760872

Roemerine is a potential active xanthine oxidase(XOD) inhibitor, XOD is a key enzyme in the pathogenesis of hyperuricemia and also a well-known target for the drug development to treat gout. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Roemerine, Inhibitor

Full Product Name

Roemerine

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

279.33

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C18H17NO2

SMILES

CN(CC1)[C@H](C2)c3c1cc1OCOc1c3-c1c2cccc1

CAS Number

548-08-3

Target & IC50

Antifection
Xanthine oxidase

In Vitro

In the current study, RNA sequencing based transcriptional profiling together with global differential protein expression analysis was used to comparatively elaborate the activities and the effects of the plant alkaloids boldine, bulbocapnine, and Roemerine along with the well-known antimicrobial alkaloid berberine in Bacillus subtilis cells. The transcriptomic findings were validated by qPCR. Images from scanning electron microscope were obtained to visualize the effects on the whole-cells[1]

Product Categories/Family for Roemerine, inhibitor

Microbiology/Virology; Antifection; Metabolic Enzyme/Protease

Product References and Citations for Roemerine, inhibitor

An OMIC approach to elaborate the antibacterial mechanisms of different alkaloids.Phytochemistry. 2018 May;149:123-131.
An OMIC approach to elaborate the antibacterial mechanisms of different alkaloids.Phytochemistry. 2018 May;149:123-131.
Modeling and optimizing inhibitory activities of Nelumbinis folium extract on xanthine oxidase using response surface methodology.J Pharm Biomed Anal. 2017 May 30;139:37-43.
New antiplasmodial alkaloids from Stephania rotunda.J Ethnopharmacol. 2013 Jan 9;145(1):381-5.

Other Notes

Small volumes of Roemerine, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Roemerine purchase

MBS5760872 is an inhibitor targeting Roemerine.