Boehmenan Inhibitor

Name: Boehmenan Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5761975
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5761975

(+/-)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5uM, it inhibits PTP1B activity in a competitive manner. Boehmenan exhibits the potent cytotoxic effects against many cancer cell… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Boehmenan, Inhibitor

Full Product Name

Boehmenan

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

712.8

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C40H40O12

CAS Number

57296-22-7

Target & IC50

Akt
Caspase
EGFR
ERK
MEK
p21
p53
PARP
PTP1B
STAT
Wnt/beta-catenin

Product Categories/Family for Boehmenan, inhibitor

Cytoskeletal Signaling; Akt; Angiogenesis; Tyrosine Kinase/Adaptors; Apoptosis; Proteases/Proteasome; Chromatin/Epigenetic; DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling; JAK/STAT signaling; Stem Cells; MAPK; Metabolic Enzyme/Protease

Product References and Citations for Boehmenan, inhibitor

Chemical constituents from Sambucus adnata and their protein-tyrosine phosphatase 1B inhibitory activities. Chem Pharm Bull (Tokyo). 2011;59(11):1396-9.
Boehmenan, a lignan from the Chinese medicinal plant Clematis armandii, induces apoptosis in lung cancer cells through modulation of EGF-dependent pathways. Phytomedicine. 2016 May 15;23(5):468-76.

Other Notes

Small volumes of Boehmenan, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Boehmenan purchase

MBS5761975 is an inhibitor targeting Boehmenan.