Isoangustone A Inhibitor

Name: Isoangustone A Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5762557
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5762557

Isoangustone A has antitumor activity, it can induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells, it inhibits cell proliferation by targeting PI3K, MKK4, and MKK7 in human melanoma. Isoangustone A dampens mesangial sclerosis… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Isoangustone A, Inhibitor

Full Product Name

Isoangustone A

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

422.47

Solubility

<1mg/ml refers to the product slightly soluble or insoluble

Formula

C25H26O6

CAS Number

129280-34-8

Target & IC50

Akt
CDK
GSK-3
JNK
MMP
NF-kappaB
PI3K
ROS
TGF-beta/Smad

Product Categories/Family for Isoangustone A, inhibitor

Cytoskeletal Signaling; Akt; Cell Cycle/Checkpoint; Immunology/Inflammation; MAPK; NF-kappab; PI3K/Akt/mTOR signaling; Stem Cells; Proteases/Proteasome

Product References and Citations for Isoangustone A, inhibitor

Hexane/ethanol extract of Glycyrrhiza uralensis and its active compound isoangustone A induce G1 cycle arrest in DU145 human prostate and 4T1 murine mammary cancer cells. J Nutr Biochem. 2012 Jan;23(1):85-92.
Antioxidant activities of licorice-derived prenylflavonoids. Nutr Res Pract. 2012 Dec;6(6):491-8.

Other Notes

Small volumes of Isoangustone A, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Isoangustone A purchase

MBS5762557 is an inhibitor targeting Isoangustone A.