(MT)-II Inhibitor – Melanotan (Mt)-II

Name: (MT)-II Inhibitor; Melanotan (Mt)-II; MyBioSource
Brand: MyBioSource
SKU: MBS5763586
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5763586

Melanotan (MT)-II, a synthetic melanocortin receptor agonist, is a synthetic analogue of the peptide hormone alpha-melanocyte-stimulating hormone (alpha-MSH). More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Melanotan (MT)-II, Inhibitor

Full Product Name

Melanotan (MT)-II

Product Gene Name

(MT)-II, inhibitor

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

1024.18

Solubility

H2O: 6.67mg/mL (6.51mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C50H69N15O9

SMILES

O=C(N[C@H](Cc1ccccc1)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@H](C(N)=O)CCCCNC(C[C@H](NC([C@@H](NC(C)=O)CCCC)=O)C(N2)=O)=O)=O)Cc(c[nH]3)c4c3cccc4)=O)=O)[C@@H]2Cc5[nH]cnc5

CAS Number

121062-08-6

Target & IC50

melanocortin receptors

In Vitro

Melanotan (MT)-II is a potent non-selective melanocortin receptor agonist with high affinity for MC1, MC3, MC4, and MC5 receptor subtypes which are involved in the regulation of a number of physiological systems such as the pigmentary system, energy homoeostasis, sexual functioning, the immune system, inflammation, and the cardiovascular system[1].

Product Categories/Family for (MT)-II, inhibitor

GPCR/G Protein; Melanocortin Receptor; Neuronal Signaling

Product References and Citations for (MT)-II, inhibitor

Breindahl T, et al. Identification and characterization by LC-UV-MS/MS of melanotan II skin-tanning products sold illegally on the Internet. Drug Test Anal. 2015 Feb;7(2):164-72.
Giuliano F, et al. Melanotan-II: Investigation of the inducer and facilitator effects on penile erection in anaesthetized rat. Neuroscience. 2006;138(1):293-301.
Ter Laak MP, et al. The potent melanocortin receptor agonist melanotan-II promotes peripheral nerve regeneration and has neuroprotective properties in the rat. Eur J Pharmacol. 2003 Feb 21;462(1-3):179-83.
Wessells H, et al. Melanocortin receptor agonists, penile erection, and sexual motivation: human studies with Melanotan II. Int J Impot Res. 2000 Oct;12 Suppl 4:S74-9.
De Jonghe BC, et al. Food intake reductions and increases in energetic responses by hindbrain leptin and melanotan II are enhanced in mice with POMC-specific PTP1B deficiency. Am J Physiol Endocrinol Metab. 2012 Sep 1;303(5):E644-51.

Other Notes

Small volumes of (MT)-II, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for (MT)-II purchase

MBS5763586 is an inhibitor targeting (MT)-II. Also known as Melanotan (MT)-II.