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TAT-cyclo-CLLFVY Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5764041

Selective HIF-1 dimerization inhibitor. Blocks protein-protein interaction of recombinant HIF-1alpha, but not HIF-2alpha, with HIF-1beta (IC50 = 1.3uM). Inhibits hypoxia-induced HIF-1 activity, and decreases VEGF and CAIX expression in osteosarcoma and breast… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TAT-cyclo-CLLFVY, Inhibitor
Full Product Name
TAT-cyclo-CLLFVY
Product Gene Name
TAT-cyclo-CLLFVY, inhibitor
Form/Format
Solid. Powder
Purity/Purification
98.00%
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
Molecular Weight
2559.1
Solubility
Water: 1mg/mL
(<1mg/ml refers to the product slightly soluble or insoluble)
Formula
C111H188N42O24S2
CAS Number
1446322-66-2

Product References and Citations for TAT-cyclo-CLLFVY, inhibitor

Miranda et al (2013) A cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells. J. Am.Chem.Soc. 135 10418 PMID:
Miranda et al (2013) A cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells. J. Am.Chem.Soc. 135 10418 PMID:

Other Notes

Small volumes of TAT-cyclo-CLLFVY, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TAT-cyclo-CLLFVY purchase

MBS5764041 is an inhibitor targeting TAT-cyclo-CLLFVY.
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