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Uromodulin (UMOD) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1443110

MBS1443110 is a recombinant protein targeting Umod. Also known as Recombinant Mouse Uromodulin (Umod). Host: E Coli or Yeast or Baculovirus or Mammalian Cell. More details

$345 / 0.02 mg (Yeast) +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Uromodulin (Umod), Recombinant Protein
Full Product Name
Recombinant Mouse Uromodulin (Umod)
Product Gene Name
Product Synonym Gene Name
Umod
Sequence
NSTEARRCSE CHNNATCTVD GVVTTCSCQT GFTGDGLVCE DMDECATPWT HNCSNSSCVN TPGSFKCSCQ DGFRLTPELS CTDVDECSEQ GLSNCHALAT CVNTEGDYLC VCPEGFTGDG WYCECSPGSC EPGLDCLPQG PDGKLVCQDP CNTYETLTEY WRSTEYGVGY SCDAGLHGWY RFTGQGGVRM AETCVPVLRC NTAAPMWLNG SHPSSSEGIV SRTACAHWSD QCCRWSTEIQ VKACPGGFYI YNLTAPPECN LAYCTDPSSV EGTCEECRVD EDCISDNGRW RCQCKQDSNI TDVSQLEYRL ECGANDIKMS LRKCQLQSLG FMNVFMYLND RQCSGFSESD ERDWMSIVTP ARNGPCGTVL RRNETHATYS NTLYLANAII IRDIIIRMNF ECSYPLDMKV SLKTSLQPMV SALNISLGGT GKFTVRMALF QSPTYTQPHQ GPSVMLSTEA FLYVGTMLDG GDLSRFVLLM TNCYATPSSN STDPVKYFII QDSCPRTEDT TIQVTENGES SQARFSVQMF RFAGNYDLVY LHCEVYLCDS TSEQCKPTCS GTRF
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE. (lot specific)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Molecular Weight
64.2 kDa
Sequence Positions
25-588aa; Partial
Tag Information
This protein contains an N-terminal tag and may also contain a C-terminal tag. Tag types are determined by various factors including tag-protein stability, please inquire for tag information.
Sterility
Sterile filter available upon request.
Endotoxin
Low endotoxin available upon request.
3D Structure
ModBase 3D Structure for Q91X17
Species
Mus musculus (Mouse)
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of Umod recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Umod. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
uromodulin preproprotein
NCBI Official Synonym Full Names
uromodulin
NCBI Official Symbol
Umod
NCBI Official Synonym Symbols
THP; Urehd1; urehr4
UniProt Protein Name
Uromodulin
UniProt Synonym Protein Names
Tamm-Horsfall urinary glycoprotein; THP
Protein Family
UniProt Gene Name
Umod
UniProt Synonym Gene Names
THP
NCBI Protein Information
uromodulin

NCBI Summary for Umod

This gene encodes a glycoprotein that is the most abundant protein in mammalian urine under physiological conditions. It is synthesized in the kidney as a glycosyl-phosphatidylinositol anchored protein and released into urine as a soluble form by proteolytic cleavage. It is thought to regulate water and salt balance in the thick ascending limb of Henle and to protect against urinary tract infection and calcium oxalate crystal formation. In mouse deficiency of this gene is associated with increased susceptibility to bacterial infections and formation of calcium crystals in kidneys. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
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UniProt Comments for Umod

Uromodulin: Functions in biogenesis and organization of the apical membrane of epithelial cells of the thick ascending limb of Henle's loop (TALH), where it promotes formation of complex filamentous gel-like structure that may play a role in the water barrier permeability. May serve as a receptor for binding and endocytosis of cytokines (IL-1, IL-2) and TNF. Facilitates neutrophil migration across renal epithelia.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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