NKP-1339 Inhibitor

Name: NKP-1339 Inhibitor; MyBioSource
Brand: MyBioSource
SKU: MBS5764274
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5764274

NKP-1339 (IT-139) induces G2/M cell cycle arrest, blockage of DNA synthesis, and induction of apoptosis via the mitochondrial pathway. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NKP-1339, Inhibitor

Full Product Name

NKP-1339

Product Gene Name

NKP-1339, inhibitor

Product Synonym Names

IT-139

Form/Format

Solid. Powder

Purity/Purification

98.00%

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Molecular Weight

502.14

Solubility

DMSO: 55mg/mL (109.53mM)
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C14H12Cl4N4NaRu

SMILES

[Cl-][Ru+3]([N]1=CC2=CC=CC=C2N1)([Cl-])([Cl-])([N]3=CC4=CC=CC=C4N3)[Cl-].[Na+]

CAS Number

197723-00-5

In Vitro

NKP-1339 can strongly bind to serum proteins such as albumin and transferrin and activates in the reductive tumor milieu.

Product Categories/Family for NKP-1339, inhibitor

DNA Damage/DNA Repair; DNA/RNA Synthesis; Apoptosis

Product References and Citations for NKP-1339, inhibitor

Robert Trondl, et al. NKP-1339, the first ruthenium-based anticancer drug on the edge to clinical application. Chemical Science. Chemical Science

Other Notes

Small volumes of NKP-1339, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NKP-1339 purchase

MBS5764274 is an inhibitor targeting NKP-1339.