Mouse Anti-ATRAID Monoclonal Antibody – Cat# MBS6005772

ATRAID Antibody – Mouse Monoclonal

Name: ATRAID Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS6005772
Price: 880 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6005772

APR3 may play a critical role in inducing the cell cycle arrest via inhibiting CCND1 expression in all-trans-retinoic acid (ATRA) signal pathway. More details

$880 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ATRAID, Monoclonal Antibody

Full Product Name

ATRAID (APR3, All-trans Retinoic Acid-induced Differentiation Factor, Apoptosis-related Protein 3, APR-3, p18, C2orf28, HSPC013, UNQ214/PRO240)

Product Gene Name

anti-ATRAID antibody

Product Synonym Names

Anti -ATRAID (APR3, All-trans Retinoic Acid-induced Differentiation Factor, Apoptosis-related Protein 3, APR-3, p18, C2orf28, HSPC013, UNQ214/PRO240)

Immunogen Sequence

MLHARCCLNQ KGTILGLDLQ NCSLEDPGPN FHQAHTTVII DLQANPLKGD LANTFRGFTQ LQTLILPQHV NCPGGINAWN TITSYIDNQI CQGQKNLCNN TGDPEMCPEN GSCVPDGPGL LQCVCADGFH GYKCMRQGSF SLLMFFGILG ATTLSVSILL WATQRRKAKT S

Clonality

Monoclonal

Isotype

IgG2a,k

Clone Number

1D2

Host

Mouse

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Recognizes human C2orf28.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

24,747 Da

Chromosome Location

Chromosome: 2; NC_000002.11 (27434899..27440046). Location: 2p23.3

3D Structure

ModBase 3D Structure for Q6UW56

Immunogen

Full length recombinant corresponding to aa1-172 from human C2orf28 (AAH11006) with GST tag. MW of the GST tag alone is 26kD.

Product Categories/Family for anti-ATRAID antibody

Antibodies; Abs to Apoptosis

Applications Tested/Suitable for anti-ATRAID antibody

ELISA (EL/EIA)

Application Notes for anti-ATRAID antibody

Suitable for use in ELISA.

Other Notes

Small volumes of anti-ATRAID antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ATRAID purchase

MBS6005772 is an antibody targeting ATRAID. Also known as ATRAID (APR3, All-trans Retinoic Acid-induced Differentiation Factor, Apoptosis-related Protein 3, APR-3, p18, C2orf28, HSPC013, UNQ214/PRO240). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for ATRAID. It may not necessarily be applicable to this product.

NCBI GI #

282847378

NCBI GeneID

51374

NCBI Accession #

NP_542159.3

UniProt Primary Accession #

Q6UW56

UniProt Secondary Accession #

Q96FF6; Q96RT2; Q9Y2R7; Q9Y5L7; A8C1S2; A8K779

UniProt Related Accession #

Q6UW56

GenBank Nucleotide #

NM_080592.3

NCBI Official Full Name

all-trans retinoic acid-induced differentiation factor isoform b

NCBI Official Synonym Full Names

all-trans retinoic acid-induced differentiation factor

NCBI Official Symbol

ATRAID

NCBI Official Synonym Symbols

p18; APR3; APR-3; APR--3; PRO240; C2orf28; HSPC013

UniProt Protein Name

All-trans retinoic acid-induced differentiation factor

UniProt Synonym Protein Names

Apoptosis-related protein 3; APR-3; p18

Protein Family

All-trans retinoic acid-induced differentiation factor

UniProt Gene Name

ATRAID

UniProt Synonym Gene Names

APR3; C2orf28; APR-3

UniProt Entry Name

ARAID_HUMAN

NCBI Protein Information

all-trans retinoic acid-induced differentiation factor; apoptosis related protein 3; apoptosis-related protein 3; apoptosis related protein APR-3

NCBI Summary for ATRAID

This gene is thought to be involved in apoptosis, and may also be involved in hematopoietic development and differentiation. The use of alternative splice sites and promotors result in multiple transcript variants encoding different isoforms.[provided by RefSeq, Dec 2009]

UniProt Comments for ATRAID

APR3: May play a critical role in inducing the cell cycle arrest via inhibiting CCND1 expression in all-trans-retinoic acid (ATRA) signal pathway. Up-regulated by all-trans-retinoic acid (ATRA) in several tumor cell lines. Weakly expressed in hematopoietic cell lines. 3 isoforms of the human protein are produced by alternative promoter.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 2p23.3

Cellular Component: perinuclear region of cytoplasm; integral to membrane; plasma membrane; nuclear envelope

Molecular Function: protein binding

Biological Process: positive regulation of osteoblast differentiation; regulation of gene expression; negative regulation of osteoblast proliferation; positive regulation of bone mineralization; cell differentiation

Research Articles on ATRAID

1. APR3 expression is increased significantly with malignant progression of human cervical cervical squamous cell carcinoma (SCC), and thus, it may serve as a potential biomarker to predict prognosis of cervical SCC.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.