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RETSAT Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6012596

MBS6012596 is an antibody targeting RETSAT. Also known as RetSat (Retinol Saturase, All-trans-retinol 13,14-reductase, All-trans-13,14-dihydroretinol Saturase, PPAR-alpha-regulated and Starvation-induced Gene Protein, PPSIG, UNQ439/PRO872). Reactive in Human.… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RetSat, Polyclonal Antibody
Full Product Name
RetSat (Retinol Saturase, All-trans-retinol 13,14-reductase, All-trans-13,14-dihydroretinol Saturase, PPAR-alpha-regulated and Starvation-induced Gene Protein, PPSIG, UNQ439/PRO872)
Product Gene Name
anti-RETSAT antibody
Product Synonym Names
Anti -RetSat (Retinol Saturase, All-trans-retinol 13,14-reductase, All-trans-13,14-dihydroretinol Saturase, PPAR-alpha-regulated and Starvation-induced Gene Protein, PPSIG, UNQ439/PRO872)
Immunogen Sequence
MHALLVNHYM KGGFYPRGGS SQIAFHTIPV IQRAGGAVLT KATVQSVLLD SAGKACGVSV KKGHELVNIY CPIVVSNAGL FNTYEHLLPG NARCLPGVKQ QLGTVRPGLG MTSVFICLRG TKEDLHLPST NYYVYYDTDM DQAMERYVSM PREEAAEHIP LLFFAFPSAK DPTWEDRFPG GECDCRIPTH QPVLSGCSPR CLLRG
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human RetSat.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
66,820 Da
Chromosome Location
Chromosome: 2; NC_000002.11 (85569078..85581821, complement). Location: 2p11.2
3D Structure
ModBase 3D Structure for Q6NUM9
Immunogen
Full length human RetSat, aa1-205 (AAH11418).

Product Categories/Family for anti-RETSAT antibody

Antibodies; Abs to Enzymes; Reductase
Applications Tested/Suitable for anti-RETSAT antibody
Western Blot (WB)
Application Notes for anti-RETSAT antibody
Suitable for use in Western Blot.

Western Blot (WB) of anti-RETSAT antibody

Western Blot analysis of RetSat expression in transfected 293T cell line by RetSat polyclonal antibody. Lane 1: RetSat transfected lysate (22.55kD). Lane 2: Non-transfected lysate.
Mouse Anti-RETSAT Polyclonal Antibody – Cat# MBS6012596

Other Notes

Small volumes of anti-RETSAT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RETSAT. It may not necessarily be applicable to this product.

NCBI GI #
15030289
NCBI GeneID
54884
NCBI Accession #
AAH11418.1
UniProt Primary Accession #
Q6NUM9
UniProt Secondary Accession #
Q53R95; Q53SA9; Q6UX05; Q8N2H5; Q96FA4; Q9NXE5; A6NIK3
UniProt Related Accession #
Q6NUM9
NCBI Official Full Name
RETSAT protein
NCBI Official Synonym Full Names
retinol saturase (all-trans-retinol 13,14-reductase)
NCBI Official Symbol
RETSAT
UniProt Protein Name
All-trans-retinol 13,14-reductase
UniProt Synonym Protein Names
All-trans-13,14-dihydroretinol saturase; RetSat; PPAR-alpha-regulated and starvation-induced gene protein
Protein Family
All-trans-retinol 13,14-reductase
UniProt Gene Name
RETSAT
UniProt Synonym Gene Names
PPSIG; RetSat
UniProt Entry Name
RETST_HUMAN
NCBI Protein Information
all-trans-retinol 13,14-reductase; all-trans-13,14-dihydroretinol saturase; PPAR-alpha-regulated and starvation-induced gene protein

UniProt Comments for RETSAT

RETSAT: Retinol saturase carrying out the saturation of the 13- 14 double bond of all-trans-retinol to produce all-trans-13,14- dihydroretinol. Has activity toward all-trans-retinol as substrate. Does not use all-trans-retinoic acid nor 9-cis, 11-cis or 13-cis-retinol isomers as substrates. May play a role in the metabolism of vitamin A. Belongs to the carotenoid/retinoid oxidoreductase family. CrtISO subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cofactor and Vitamin Metabolism - retinol; Secreted, signal peptide; EC 1.3.99.23; Oxidoreductase; Secreted

Chromosomal Location of Human Ortholog: 2p11.2

Cellular Component: nuclear outer membrane; endoplasmic reticulum membrane; nuclear membrane; membrane

Molecular Function: all-trans-retinol 13,14-reductase activity; oxidoreductase activity

Biological Process: retinol metabolic process
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Research Articles on RETSAT

1. RetSat plays an important role in the biology of adipocytes, where it favors normal differentiation, yet is reduced in the obese state.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RETSAT antibody

 Reference Product  PubMed Publications
 RDH10 antibody  >1 publications with RETSAT and RDH10
 LRAT antibody  >1 publications with RETSAT and LRAT
 CYP26A1 antibody  >1 publications with RETSAT and CYP26A1

Pathways associated with anti-RETSAT antibody

 Products by Pathway  Pathway Diagram
 Retinol Metabolism Pathway antibodies  Retinol Metabolism Pathway Diagram
 Retinol Metabolism Pathway antibodies  Retinol Metabolism Pathway Diagram
 Vitamin A And Carotenoid Metabolism Pathway antibodies  Vitamin A And Carotenoid Metabolism Pathway Diagram

Diseases associated with anti-RETSAT antibody

 Disease Name  Pubmed Publications
 Weight Gain Antibodies  >1 publications with RETSAT and Weight Gain
 Disease Models, Animal Antibodies  >1 publications with RETSAT and Disease Models, Animal
 Fatty Liver Antibodies  >1 publications with RETSAT and Fatty Liver

Organs/Tissues associated with anti-RETSAT antibody

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >5 publications with RETSAT and Liver
 Adipose Tissue Antibodies  >3 publications with RETSAT and Adipose Tissue
 Intestine Antibodies  >2 publications with RETSAT and Intestine
 Connective Tissue Antibodies  >1 publications with RETSAT and Connective Tissue
 Thymus Antibodies  >1 publications with RETSAT and Thymus
 Kidney Antibodies  >1 publications with RETSAT and Kidney
 Brain Antibodies  >1 publications with RETSAT and Brain
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