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Arginine-Glutamic Acid Dipeptide (RERE) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS601558

This gene encodes a member of the atrophin family of arginine-glutamic acid (RE) dipeptide repeat-containing proteins. The encoded protein co-localizes with a transcription factor in the nucleus, and its overexpression triggers apoptosis. A similar protein in… More details

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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Arginine-Glutamic Acid Dipeptide (RERE), Monoclonal Antibody
Full Product Name
Arginine-Glutamic Acid Dipeptide (RE) Repeats (RERE)
Product Gene Name
anti-RERE antibody
Product Synonym Names
Anti -Arginine-Glutamic Acid Dipeptide (RE) Repeats (RERE)
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
8C14
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.4, 1% BSA, 0.05% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human Arginine-Glutamic Acid Dipeptide (RE) Repeats.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 
Molecular Weight
172,424 Da
Chromosome Location
Chromosome: 1; NC_000001.10 (8412464..8877699, complement). Location: 1p36.23
OMIM
605226
3D Structure
ModBase 3D Structure for Q9P2R6
Immunogen
Partial recombinant sequence corresponding to human RERE.

Product Categories/Family for anti-RERE antibody

Antibodies; Abs to Peptides
Applications Tested/Suitable for anti-RERE antibody
Western Blot (WB), Gel Shift Assay (GS/EMSA)
Application Notes for anti-RERE antibody
Suitable for use in Western Blot and Dot Blot.

Other Notes

Small volumes of anti-RERE antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RERE purchase

MBS601558 is an antibody targeting RERE. Also known as Arginine-Glutamic Acid Dipeptide (RE) Repeats (RERE). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for RERE. It may not necessarily be applicable to this product.

NCBI GI #
112382226
NCBI GeneID
473
NCBI Accession #
NP_001036147.1
UniProt Primary Accession #
Q9P2R6
UniProt Secondary Accession #
O43393; O75046; O75359; Q5VXL9; Q6P6B9; Q9Y2W4
UniProt Related Accession #
Q9P2R6
GenBank Nucleotide #
NM_001042682.1
NCBI Official Full Name
arginine-glutamic acid dipeptide repeats protein isoform b
NCBI Official Synonym Full Names
arginine-glutamic acid dipeptide (RE) repeats
NCBI Official Symbol
RERE
NCBI Official Synonym Symbols
ARG; ARP; DNB1; ATN1L; FLJ38775; KIAA0458
UniProt Protein Name
Arginine-glutamic acid dipeptide repeats protein
UniProt Synonym Protein Names
Atrophin-1-like protein; Atrophin-1-related protein
Protein Family
Arginine-glutamic acid dipeptide repeats protein
UniProt Gene Name
RERE
UniProt Synonym Gene Names
ARG; ARP; ATN1L; KIAA0458
UniProt Entry Name
RERE_HUMAN
NCBI Protein Information
arginine-glutamic acid dipeptide repeats protein; atrophin 2; OTTHUMP00000001701; OTTHUMP00000001702; OTTHUMP00000221011; OTTHUMP00000221012; OTTHUMP00000221015; atrophin-1 like protein; atrophin-1-like protein; atrophin-1 related protein; atrophin-1-related protein

UniProt Comments for RERE

RERE: Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death. A chromosomal aberration involving RERE is found in the neuroblastoma cell line. Translocation t(1;15)(p36.2;q24). 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Nuclear receptor co-regulator; Transcription factor

Chromosomal Location of Human Ortholog: 1p36.23

Cellular Component: histone deacetylase complex; nucleus

Molecular Function: protein binding; zinc ion binding; sequence-specific DNA binding; poly-glutamine tract binding; chromatin binding; transcription factor activity

Biological Process: chromatin remodeling; regulation of transcription, DNA-dependent; transcription, DNA-dependent; multicellular organismal development; NLS-bearing substrate import into nucleus
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Research Articles on RERE

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RERE antibody

 Reference Product  PubMed Publications
 ATN1 antibody  >2 publications with RERE and ATN1

Diseases associated with anti-RERE antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >6 publications with RERE and Neoplasms
 Nervous System Diseases Antibodies  >2 publications with RERE and Nervous System Diseases
 Recurrence Antibodies  >2 publications with RERE and Recurrence
 Lung Neoplasms Antibodies  >1 publications with RERE and Lung Neoplasms
 Arteriosclerosis Antibodies  >1 publications with RERE and Arteriosclerosis
 Spinal Cord Injuries Antibodies  >1 publications with RERE and Spinal Cord Injuries
 Abdominal Neoplasms Antibodies  >1 publications with RERE and Abdominal Neoplasms
 Genetic Diseases, Inborn Antibodies  >1 publications with RERE and Genetic Diseases, Inborn
 Edema Antibodies  >1 publications with RERE and Edema
 Melanoma Antibodies  >1 publications with RERE and Melanoma

Organs/Tissues associated with anti-RERE antibody

 Organ/Tissue Name  Pubmed Publications
 Nerve Antibodies  >7 publications with RERE and Nerve
 Bone Antibodies  >3 publications with RERE and Bone
 Liver Antibodies  >2 publications with RERE and Liver
 Embryonic Tissue Antibodies  >2 publications with RERE and Embryonic Tissue
 Lung Antibodies  >2 publications with RERE and Lung
 Vascular Antibodies  >1 publications with RERE and Vascular
 Skin Antibodies  >1 publications with RERE and Skin
 Heart Antibodies  >1 publications with RERE and Heart
 Blood Antibodies  >1 publications with RERE and Blood
 Bladder Antibodies  >1 publications with RERE and Bladder
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