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NSC-687852, UCHL5 inhibitor (3,5-bis[(4-nitrophenyl)methylidene]-1-prop-2-enoylpiperidin-4-one, (3E,5E)-3,5-bis[(4-nitrophenyl)methylene]-1-prop-2-enoyl-piperidin-4-one, b-AP15)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6017748

Cell-permeable. Abrogates the deubiquitinating activity of the 19S regulatory particle by inhibiting ubiquitin C-terminal hydrolase 5 (UCHL5) and ubiquitin-specific peptidase 14 (USP14) resulting in accumulation of polyubiquitin in cells. NSC-687852 induces… More details

$355 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NSC-687852, UCHL5 inhibitor, Biochemical
Full Product Name
NSC-687852, UCHL5 inhibitor (3,5-bis[(4-nitrophenyl)methylidene]-1-prop-2-enoylpiperidin-4-one, (3E,5E)-3,5-bis[(4-nitrophenyl)methylene]-1-prop-2-enoyl-piperidin-4-one, b-AP15)
Sequence
3,5-bis[(4 -nitrophen yl)methyli dene]-1-pr op-2-enoyl piperidin- 4-one
Form/Format
Supplied as a pale yellow solid.
Purity/Purification
Highly Purified
~98% (HPLC)
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
419.39
Molecular Formula
C22H17N3O6
Solubility
DMSO (~35mg/ml)

Product Categories/Family for NSC-687852, UCHL5 inhibitor biochemical

Biochemicals; Biochem-Inhibitors

Structure of NSC-687852, UCHL5 inhibitor biochemical

Structure of N5392-32
NSC-687852, UCHL5 inhibitor (3,5-bis[(4-nitrophenyl)methylidene]-1-prop-2-enoylpiperidin-4-one, (3E,5E)-3,5-bis[(4-nitrophenyl)methylene]-1-prop-2-enoyl-piperidin-4-one, b-AP15) Biochemical – Cat# MBS6017748

Other Notes

Small volumes of NSC-687852, UCHL5 inhibitor biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NSC-687852, UCHL5 inhibitor purchase

MBS6017748 is a biochemical targeting NSC-687852, UCHL5 inhibitor. Also known as NSC-687852, UCHL5 inhibitor (3,5-bis[(4-nitrophenyl)methylidene]-1-prop-2-enoylpiperidin-4-one, (3E,5E)-3,5-bis[(4-nitrophenyl)methylene]-1-prop-2-enoyl-piperidin-4-one, b-AP15).
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