Mouse Anti-LOC100533357 Monoclonal Antibody – Cat# MBS602388

Formalin-fixed, paraffin-embedded human rectum stained with MBS602388 using peroxidase-conjugate and AEC chromogen. Note cytoplasmic staining of smooth muscles.

Actin, Muscle Specic (LOC100533357) Antibody – Mouse Monoclonal

Name: LOC100533357 Antibody; Monoclonal; Mouse; MyBioSource
Brand: MyBioSource
SKU: MBS602388
Price: 655 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS602388

Actin is a major component of the cytoskeleton. Actin can be resolved on the basis of its isoelectric points into three distinctive components: alpha, beta, and gamma in order of increasing isoelectric point. Anti-Muscle-Specific Actin recognizes alpha and… More details

$655 / 0.5 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Actin, Muscle Specic (LOC100533357), Monoclonal Antibody

Full Product Name

Actin, Muscle Specic

Product Gene Name

anti-LOC100533357 antibody

Product Synonym Names

Anti -Actin, Muscle Speci c

Clonality

Monoclonal

Isotype

IgG1,k

Clone Number

3F10

Host

Mouse

Species Reactivity

Bovine, Canine, Equine, Human, Mouse, Porcine, Rat

Form/Format

Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide. Also available without BSA and azide., See A0760-22AX.

Purity/Purification

Affinity Purified
Purified by Protein G affinity chromatography.

Specificity

Recognizes alpha-smooth muscle, alpha-skeletal and alpha-cardiac (sarcomeric) isoforms of human actin. Reacts with tumors arising from smooth muscle (leiomyosarcomas) and skeletal muscle (rhabdomyosarcomas). Species Crossreactivity: mouse, rat, porcine, equine, bovine and canine.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

41,766 Da

Chromosome Location

chromosome: Un

3D Structure

ModBase 3D Structure for P17304

Immunogen

Purified actin. Cellular Localization: Cytoplasmic.

Positive Control

Muscle or sarcoma

Product Categories/Family for anti-LOC100533357 antibody

Antibodies; Abs to Actin Related Proteins

Applications Tested/Suitable for anti-LOC100533357 antibody

Immunohistochemistry (IHC), Immunofluorescence (IF)

Application Notes for anti-LOC100533357 antibody

Suitable for use in Immunofluorescence and Immunohistochemistry.
Dilution: Immunohistochemistry (Formalin/paraffin): 1-2ug/ml for 30 minutes at RT. No special pretreatment is required for immunohistochemical staining of formalin-fixed tissues.

Other Notes

Small volumes of anti-LOC100533357 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LOC100533357 purchase

MBS602388 is an antibody targeting LOC100533357. Also known as Actin, Muscle Specic. Reactive in Bovine, Canine, Equine, Human, Mouse, Porcine, Rat. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for LOC100533357. It may not necessarily be applicable to this product.

NCBI GI #

325297142

NCBI GeneID

100533357

NCBI Accession #

NP_001191580.1

UniProt Primary Accession #

P17304

UniProt Related Accession #

P17304

GenBank Nucleotide #

NM_001204651.1

NCBI Official Full Name

actin, muscle

NCBI Official Symbol

LOC100533357

UniProt Protein Name

Actin, muscle

UniProt Entry Name

ACTM_APLCA

NCBI Protein Information

actin, muscle

UniProt Comments for LOC100533357

Function: Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.Multiple isoforms are involved in various cellular functions such as cytoskeleton structure, cell mobility, chromosome movement and muscle contraction.

Subunit structure: Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to 4 others.

Subcellular location: Cytoplasm › cytoskeleton.

Tissue specificity: Expressed in the muscular cells of the sheath surrounding abdominal ganglions.

Sequence similarities: Belongs to the actin family.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.