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Ganglioside GD3 (siat8a) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS603896

GD3 has been identified as tumor-associated antigens expressed on the surface of neuroectoderm-derived tumors (melanoma, neuroblastoma and glioma) and T-cell leukemia. Gangliosides (sialic acid-containing glycosphingolipids) are normal membrane constituents… More details

$965 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Ganglioside GD3 (siat8a), Monoclonal Antibody
Full Product Name
Ganglioside GD3
Product Gene Name
Product Synonym Names
Anti -Ganglioside GD3
Clonality
Monoclonal
Isotype
IgG3
Clone Number
2Q631
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.6, 0.09% sodium azide.
Purity/Purification
Purified by Protein A affinity chromatography from ascites.
Concentration
1 mg/mL (lot specific)
Specificity
Recognizes human Ganglioside GD3. Does not crossreact with other gangliosides purified from neuroblastoma or melanoma cells.
Preparation and Storage
May be stored at 4°C. For long term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the orinal vial prior to removing the cap. Further dilutions can be made in assay buffer.
3D Structure
ModBase 3D Structure for Q5K022
Immunogen
FM9 melanoma cells
Grade
Affinity Purified
Applications Tested/Suitable for anti-siat8a antibody
Suitable for use in Flow Cytometry, Immunofluorescence and Immunohistochemistry. Other applications not tested.
Application Notes for anti-siat8a antibody
Flow Cytometry: 1-2ug/ml per 10e6 cells cells. Lysis of GD3 positive (melanoma) cells in presence of complement.

Immunohistochemistry: Frozen tissue sections

Immunofluorescence: Cells in culture

Optimal dilutions to be determined by the researcher.

Other Notes

Small volumes of anti-siat8a antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for siat8a purchase

MBS603896 is an antibody targeting siat8a. Also known as Ganglioside GD3. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for siat8a. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
NCBI Official Full Name
ganglioside GD3 synthase
NCBI Official Symbol
siat8a
NCBI Official Synonym Symbols
St8sia1
UniProt Protein Name
Ganglioside GD3 synthase
UniProt Gene Name
siat8a
UniProt Entry Name
Q5K022_ORYLA
NCBI Protein Information
alpha-2,8-sialyltransferase 1

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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