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CaMK2 alpha/delta Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9504085

MBS9504085 is an antibody targeting CaMK2 alpha/delta. Also known as CaMK2 alpha/delta Antibody. Reactive in Human, Mouse, Rat. Host: Rabbit. More details

$300 / 0.05 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CaMK2 alpha/delta, Polyclonal Antibody
Full Product Name
CaMK2 alpha/delta Antibody
Product Synonym Gene Name
CAMK2D
Product Synonym Names
CAMK2A; CaM-kinase II alpha chain; CaMK-II alpha subunit; CaMKII-alpha; Calcium/calmodulin-dependent protein kinase type II alpha chain; KCC2A; kinase CaMK2-alpha
Clonality
Polyclonal
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Form/Format
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Purified from rabbit antiserum by affinity-chromatography using immunogen.
Concentration
1 mg/ml (lot specific)
Specificity
CaMK2 alpha/delta Antibody detects endogenous levels of total CaMK2 alpha/delta protein.
Preparation and Storage
Stable at -20 degree C for at least 1 year.
Molecular Weight
54 kDa
OMIM
AF145710 mRNA
3D Structure
ModBase 3D Structure for Q9UQM7
Target Modification
Unmodified/Total
Immunogen
The antiserum was produced against synthesized peptide derived from human CaMK2 alpha/delta.
Immunogen Range
256-305
Applications Tested/Suitable for anti-CaMK2 alpha/delta antibody
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-CaMK2 alpha/delta antibody
WB: 1:500~1:1000
IHC: 1:50~1:100
IF: 1:100~1:500
ELISA: 1:10000

Immunofluorescence (IF) of anti-CaMK2 alpha/delta antibody

Immunofluorescence analysis of MCF7 cells, using CaMK2 alpha/delta Antibody. The picture on the right is blocked with the synthesized peptide.
Rabbit Anti-CaMK2 alpha/delta Polyclonal Antibody – Cat# MBS9504085

Immunohistochemistry (IHC) of anti-CaMK2 alpha/delta antibody

Immunohistochemistry analysis of paraffin-embedded human brain tissue, using CaMK2 alpha/delta Antibody. The picture on the right is blocked with the synthesized peptide.
Rabbit Anti-CaMK2 alpha/delta Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS9504085

Western Blot (WB) of anti-CaMK2 alpha/delta antibody

Western blot analysis of lysates from NIH/3T3 and K562 cells, using CaMK2 alpha/delta Antibody. The lane on the right is blocked with the synthesized peptide.
Rabbit Anti-CaMK2 alpha/delta Polyclonal Antibody, Western Blot (WB) – Cat# MBS9504085

Other Notes

Small volumes of anti-CaMK2 alpha/delta antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CaMK2 alpha/delta. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
calcium/calmodulin-dependent protein kinase type II subunit alpha isoform 2
NCBI Official Synonym Full Names
calcium/calmodulin dependent protein kinase II alpha
NCBI Official Symbol
CAMK2A
NCBI Official Synonym Symbols
CAMKA; MRD53
UniProt Protein Name
Calcium/calmodulin-dependent protein kinase type II subunit alpha
UniProt Gene Name
CAMK2A
UniProt Synonym Gene Names
CAMKA; KIAA0968; CaM kinase II subunit alpha; CaMK-II subunit alpha
NCBI Protein Information
calcium/calmodulin-dependent protein kinase type II subunit alpha

NCBI Summary for CaMK2 alpha/delta

The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008]
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UniProt Comments for CaMK2 alpha/delta

CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity (). Phosphorylates transcription factor FOXO3 on 'Ser-298' (PubMed:23805378). Activates FOXO3 transcriptional activity ().
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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