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3-Hydroxybutyrate Dehydrogenase, Type 1 (BDH1) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS604976

BDH1 (3-hydroxybutyrate dehydrogenase, type 1), it is a member of the short-chain dehydrogenase/reductase gene family. This protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for… More details

$790 / 0.1 mL +1 FREE 8GB USB
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Product Overview

Online Datasheet in PDF
Product Name
3-hydroxybutyrate dehydrogenase, type 1 (BDH1), Monoclonal Antibody
Full Product Name
3-hydroxybutyrate dehydrogenase, type 1 (3-hydroxybutyrate dehydrogenase, BDH, BDH1, D-beta-hydroxybutyrate dehydrogenase, mitochondrial, MGC2723, MGC4347, MGC9788, SDR9C1)
Product Gene Name
anti-BDH1 antibody
Product Synonym Names
Anti -3-hydroxybutyrate dehydrogenase, type 1 (3-hydroxybutyrate dehydrogenase, BDH, BDH1, D-beta-hydroxybutyrate dehydrogenase, mitochondrial, MGC2723, MGC4347, MGC9788, SDR9C1)
Clonality
Monoclonal
Isotype
IgG1
Clone Number
10F603
Host
Mouse
Species Reactivity
Human, Mouse
Form/Format
Supplied as liquid, 0.04% sodium azide.
Purity/Purification
Ascites
Ascites
Specificity
Recognizes human 3-hydroxybutyrate dehydrogenase, type 1 at 38kD. Species Crossreactivity: mouse.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
38,157 Da
Chromosome Location
Chromosome: 3; NC_000003.11 (197236654..197300194, complement). Location: 3q29
OMIM
603063
3D Structure
ModBase 3D Structure for Q02338
Immunogen
Purified recombinant fragment of human 3-hydroxybutyrate dehydrogenase, type 1 expressed in E. coli.

Product Categories/Family for anti-BDH1 antibody

Antibodies; Abs to Enzymes; Dehydrogenase
Applications Tested/Suitable for anti-BDH1 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-BDH1 antibody
Suitable for use in ELISA, Western Blot and Immunohistochemistry.
Dilution: ELISA: 1:10,000
Western Blot: 1:500-1:2000
Immunohistochemistry (Paraffin): 1:200-1:1000

Western Blot (WB) of anti-BDH1 antibody

Western blot analysis using MBS604976 against HepG2 (1) and NIH/3T3 (2) cell lysate.
Mouse Anti-BDH1 Monoclonal Antibody – Cat# MBS604976

Western Blot (WB) of anti-BDH1 antibody

Western blot analysis using MBS604976 against BDH1 (aa47-343)-hIgGFc transfected HEK293 cell lysate (1).
Mouse Anti-BDH1 Monoclonal Antibody, Western Blot (WB) – Cat# MBS604976

Immunohistochemistry (IHC) of anti-BDH1 antibody

Immunohistochemical analysis of paraffin-embedded human liver cancer (left) and colorectal cancer tissues (right) using H0529-18with DAB staining.
Mouse Anti-BDH1 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS604976

Other Notes

Small volumes of anti-BDH1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BDH1 purchase

MBS604976 is an antibody targeting BDH1. Also known as 3-hydroxybutyrate dehydrogenase, type 1 (3-hydroxybutyrate dehydrogenase, BDH, BDH1, D-beta-hydroxybutyrate dehydrogenase, mitochondrial, MGC2723, MGC4347, MGC9788, SDR9C1). Reactive in Human, Mouse. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for BDH1. It may not necessarily be applicable to this product.

NCBI GI #
17939514
NCBI GeneID
622
UniProt Primary Accession #
Q02338
UniProt Secondary Accession #
Q96ET1; Q9BRZ4; D3DXC0
UniProt Related Accession #
Q02338
NCBI Official Full Name
3-hydroxybutyrate dehydrogenase, type 1
NCBI Official Synonym Full Names
3-hydroxybutyrate dehydrogenase, type 1
NCBI Official Symbol
BDH1
NCBI Official Synonym Symbols
BDH; SDR9C1; MGC2723; MGC4347; MGC9788
UniProt Protein Name
D-beta-hydroxybutyrate dehydrogenase, mitochondrial
UniProt Synonym Protein Names
3-hydroxybutyrate dehydrogenase
Protein Family
(R,R)-butanediol dehydrogenase
UniProt Gene Name
BDH1
UniProt Synonym Gene Names
BDH
UniProt Entry Name
BDH_HUMAN
NCBI Protein Information
D-beta-hydroxybutyrate dehydrogenase, mitochondrial; OTTHUMP00000208056; OTTHUMP00000208057; OTTHUMP00000208058; OTTHUMP00000208059; (R)-3-hydroxybutyrate dehydrogenase; 3-hydroxybutyrate dehydrogenase (heart, mitochondrial); short chain dehydrogenase/reductase family 9C, member 1

NCBI Summary for BDH1

This gene encodes a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq]
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UniProt Comments for BDH1

BDH: a member of the short-chain dehydrogenase/reductase gene family. The encoded protein forms a homotetrameric lipid-requiring enzyme of the mitochondrial membrane and has a specific requirement for phosphatidylcholine for optimal enzymatic activity. The encoded protein catalyzes the interconversion of acetoacetate and (R)-3-hydroxybutyrate, the two major ketone bodies produced during fatty acid catabolism. Alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Jul 2008]

Protein type: Mitochondrial; Lipid Metabolism - synthesis and degradation of ketone bodies; Oxidoreductase; EC 1.1.1.30; Carbohydrate Metabolism - butanoate

Chromosomal Location of Human Ortholog: 3q29

Cellular Component: nucleoplasm; mitochondrion; mitochondrial matrix; cytoplasm; mitochondrial inner membrane

Molecular Function: 3-hydroxybutyrate dehydrogenase activity; phospholipid binding

Biological Process: response to drug; response to toxin; ketone body metabolic process; cellular lipid metabolic process; liver development; response to estradiol stimulus; response to insulin stimulus; response to starvation; response to cadmium ion; response to ethanol; ketone body catabolic process; ketone body biosynthetic process; brain development; response to nutrient; response to corticosterone stimulus
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Research Articles on BDH1

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-BDH1 antibody

 Products by Pathway  Pathway Diagram
 Butanoate Metabolism Pathway antibodies  Butanoate Metabolism Pathway Diagram
 Butanoate Metabolism Pathway antibodies  Butanoate Metabolism Pathway Diagram
 FOXA2 And FOXA3 Transcription Factor Networks Pathway antibodies  FOXA2 And FOXA3 Transcription Factor Networks Pathway Diagram
 Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway antibodies  Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway Diagram
 Ketone Body Metabolism Pathway antibodies  Ketone Body Metabolism Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Metabolism Of Lipids And Lipoproteins Pathway antibodies  Metabolism Of Lipids And Lipoproteins Pathway Diagram
 Synthesis And Degradation Of Ketone Bodies Pathway antibodies  Synthesis And Degradation Of Ketone Bodies Pathway Diagram
 Synthesis And Degradation Of Ketone Bodies Pathway antibodies  Synthesis And Degradation Of Ketone Bodies Pathway Diagram
 Synthesis And Degradation Of Ketone Bodies Pathway antibodies  Synthesis And Degradation Of Ketone Bodies Pathway Diagram

Diseases associated with anti-BDH1 antibody

 Disease Name  Pubmed Publications
 Glioma Antibodies  >1 publications with BDH1 and Glioma
 Drug Toxicity Antibodies  >1 publications with BDH1 and Drug Toxicity

Organs/Tissues associated with anti-BDH1 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >2 publications with BDH1 and Blood
 Muscle Antibodies  >1 publications with BDH1 and Muscle
 Heart Antibodies  >1 publications with BDH1 and Heart
 Liver Antibodies  >1 publications with BDH1 and Liver
 Mammary Gland Antibodies  >1 publications with BDH1 and Mammary Gland
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