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DDX6 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS607071

This gene encodes a member of the DEAD box protein family. The protein is an RNA helicase found in P-bodies and stress granules, and functions in translation suppression and mRNA degradation. It is required for microRNA-induced gene silencing. More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DDX6, Monoclonal Antibody
Full Product Name
DDX6 (DDX-6, DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6, DEAD Box Protein 6, FLJ36338, HLR2, HLR-2, P54 RNA Helicase, RCK) (Azide Free)
Product Gene Name
Product Synonym Names
Anti -DDX6 (DDX-6, DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6, DEAD Box Protein 6, FLJ36338, HLR2, HLR-2, P54 RNA Helicase, RCK) (Azide Free)
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
10B2681
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added.
Purity/Purification
Purified
Purified by ammonium sulfate precipitation.
Specificity
Recognizes human DDX6 at ~54kD.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
54,417 Da
Chromosome Location
Chromosome: 11; NC_000011.9 (118618472..118661972, complement). Location: 11q23.3
OMIM
600326
3D Structure
ModBase 3D Structure for P26196
Immunogen
Recombinant protein corresponding to aa1-484 of human DDX6 with a GST tag (26kD).
Applications Tested/Suitable for anti-DDX6 antibody
ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-DDX6 antibody
Suitable for use in ELISA, Immunohistochemistry and Western Blot.
Dilution: Immunohistochemistry: 1.5ug/ml
ELISA: 1ug/ml-3ng/ml
Western Blot: 1:500-1:1000

Other Notes

Small volumes of anti-DDX6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DDX6 purchase

MBS607071 is an antibody targeting DDX6. Also known as DDX6 (DDX-6, DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 6, DEAD Box Protein 6, FLJ36338, HLR2, HLR-2, P54 RNA Helicase, RCK) (Azide Free). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for DDX6. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
DDX6 protein
NCBI Official Synonym Full Names
DEAD (Asp-Glu-Ala-Asp) box polypeptide 6
NCBI Official Symbol
DDX6
NCBI Official Synonym Symbols
P54; RCK; HLR2; FLJ36338
UniProt Protein Name
Probable ATP-dependent RNA helicase DDX6
UniProt Synonym Protein Names
ATP-dependent RNA helicase p54; DEAD box protein 6; Oncogene RCK
UniProt Gene Name
DDX6
UniProt Synonym Gene Names
HLR2; RCK
UniProt Entry Name
DDX6_HUMAN
NCBI Protein Information
probable ATP-dependent RNA helicase DDX6; DEAD box-6; oncogene RCK; DEAD box protein 6; OTTHUMP00000232837; OTTHUMP00000232838; ATP-dependent RNA helicase p54; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 6 (RNA helicase, 54kD)

UniProt Comments for DDX6

DDX6: an oncogenic ATP-dependent helicase of the DEAD box family. Interacts with argonaute proteins, Ago1 and Ago2, and is a general repressor of translation in human cells by miRNA-induced gene silencing. In the process of mRNA degradation, may play a role in mRNA decapping.

Protein type: RNA-binding; EC 3.6.4.13; Oncoprotein; RNA processing; Helicase

Chromosomal Location of Human Ortholog: 11q23.3

Cellular Component: membrane; intracellular membrane-bound organelle; stress granule; cytoplasm; cytosol

Molecular Function: protein domain specific binding; protein binding; helicase activity; RNA helicase activity; ATP binding

Biological Process: cytoplasmic mRNA processing body assembly; gene expression; mRNA catabolic process, deadenylation-dependent decay
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-DDX6 antibody

 Reference Product  PubMed Publications
 EDC3 antibody  >2 publications with DDX6 and EDC3
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