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DAPT (N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-Butyl Ester)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6081705

Cell permeable. A potent inhibitor of g-secretase (IC 5nM for total b-amyloid, IC = 200 nM for b-amyloid 1-42). It reduces Ab levels in vivo in plasma and cerebrospinal fluid in young and aged Tg2576 mice. Antagonizes Notch signaling through inhibition of… More details

$510 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DAPT, Biochemical
Full Product Name
DAPT (N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-Butyl Ester)
Form/Format
Supplied as a white to off-white solid.
Purity/Purification
Highly Purified
~98% (TLC)
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
~432.46
CAS Number
208255-80-5
Molecular Formula
C??H??F?N?O?
Solubility
DMSO (~20mg/ml)

Product Categories/Family for DAPT biochemical

Biochemicals; Biochem-Inhibitors

Testing Data of DAPT biochemical

(S)-Tert-butyl 2-((S)-2-(2-(3,5-difluorophenyl)acetamido)propanamido)-2-phenylacetate; N-S-phenylglycine tert.butyl ester; GSI-IX; Secretase, gamma Inhibitor IX
DAPT (N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-Butyl Ester) Biochemical – Cat# MBS6081705

Other Notes

Small volumes of DAPT biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DAPT purchase

MBS6081705 is a biochemical targeting DAPT. Also known as DAPT (N-[N-(3,5-Difluorophenacetyl-L-alanyl)]-S-phenylglycine t-Butyl Ester).
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