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Lysosome-Associated Membrane Protein-1 (LAMP1) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS608184

LAMP1 (Lysosome-associated membrane protein-1; also known as CD107a) is a 100-130kD member of the LAMP family of glycoproteins. It is expressed in lysosomal and plasma membranes of macrophages, NK and T cells, and is essential for the formation of… More details

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Testing Data View PDF
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Product Overview

Online Datasheet in PDF
Product Name
Lysosome-associated Membrane Protein-1 (LAMP1), Monoclonal Antibody
Full Product Name
Lysosome-associated Membrane Protein-1 (LAMP1, LAMP-1, CD107a Antigen, LAMPA, LGP120, Lysosome-associated Membrane Glycoprotein 1 Precursor) (PE)
Product Gene Name
Product Synonym Names
Anti -Lysosome-associated Membrane Protein-1 (LAMP1, LAMP-1, CD107a Antigen, LAMPA, LGP120, Lysosome-associated Membrane Glycoprotein 1 Precursor) (PE)
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
9H151
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a lyophilized powder in 25ug antibody, 1ml saline, 0.5% BSA, 0.1% sodium azide. Reconstitute with 40-50% glycerol, PBS.
Purity/Purification
Affinity Purified
Purified by Protein G affinity chromatography.
Specificity
Recognizes human LAMP-1.
Preparation and Storage
Maybe stored at 4 degree C before opening. DO NOT FREEZE! Stable at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. Stable for at least 6 months at 4 degree C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.
Molecular Weight
44,882 Da
Chromosome Location
Chromosome: 13; NC_000013.10 (113951436..113977746). Location: 13q34
OMIM
153330
3D Structure
ModBase 3D Structure for P11279
Immunogen
NS0-derived, recombinant human LAMP-1 aa 28-380.

Product Categories/Family for anti-LAMP1 antibody

Applications Tested/Suitable for anti-LAMP1 antibody
Flow Cytometry (FC/FACS)
Application Notes for anti-LAMP1 antibody
Suitable for use in Flow Cytometry.

Testing Data of anti-LAMP1 antibody

THP-1 cells were stained with PE-conjugated anti-human LAMP1/CD107a | or isotype control .
Mouse Anti-LAMP1 Monoclonal Antibody – Cat# MBS608184

Other Notes

Small volumes of anti-LAMP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LAMP1 purchase

MBS608184 is an antibody targeting LAMP1. Also known as Lysosome-associated Membrane Protein-1 (LAMP1, LAMP-1, CD107a Antigen, LAMPA, LGP120, Lysosome-associated Membrane Glycoprotein 1 Precursor) (PE). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for LAMP1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
lysosome-associated membrane glycoprotein 1
NCBI Official Synonym Full Names
lysosomal-associated membrane protein 1
NCBI Official Symbol
LAMP1
NCBI Official Synonym Symbols
LAMPA; CD107a; LGP120
UniProt Protein Name
Lysosome-associated membrane glycoprotein 1
UniProt Synonym Protein Names
CD107 antigen-like family member A
UniProt Gene Name
LAMP1
UniProt Synonym Gene Names
LAMP-1
UniProt Entry Name
LAMP1_HUMAN
NCBI Protein Information
lysosome-associated membrane glycoprotein 1; LAMP-1; CD107 antigen-like family member A; lysosome-associated membrane protein 1

NCBI Summary for LAMP1

The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008]

UniProt Comments for LAMP1

LAMP1: Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis. Belongs to the LAMP family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 13q34

Cellular Component: integral to plasma membrane; lysosome; dendrite; multivesicular body; membrane; cell soma; cytoplasm; late endosome; plasma membrane; melanosome; endosome membrane; sarcolemma; external side of plasma membrane

Molecular Function: protein domain specific binding; protein binding; enzyme binding

Biological Process: positive regulation of natural killer cell degranulation; induction of apoptosis by granzyme; protein stabilization; viral reproduction; autophagic cell death; autophagy; positive regulation of natural killer cell mediated cytotoxicity
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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