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MK-2206 (8-(4-(1-Aminocyclobutyl)phenyl-9-phenyl[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one DiHydrochloride)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6101332

A highly selective non-ATP competitive allosteric Akt inhibitor with IC 's of 8 nM, 2 nM and 65 nM for Akt1, Akt2 and Akt3, respectively. MK-2206 potently inhibits phosphorylation of Thr³ and Ser ³ in 3T3-L1 adipocytes with IC values of 0.11 and 0.18 µM,… More details

$425 / 0.5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MK-2206, Biochemical
Full Product Name
MK-2206 (8-(4-(1-Aminocyclobutyl)phenyl-9-phenyl[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one Dihydrochloride)
Form/Format
Supplied as a crystalline solid.
Purity/Purification
Highly Purified
~98% (HPLC)
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with DMSO. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
~480.39
CAS Number
1032350-13-2
Molecular Formula
C??H??N?O.2HCl
Solubility
DMSO

Other Notes

Small volumes of MK-2206 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MK-2206 purchase

MBS6101332 is a biochemical targeting MK-2206. Also known as MK-2206 (8-(4-(1-Aminocyclobutyl)phenyl-9-phenyl[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one Dihydrochloride).
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