Kinesin 2 (KNS2) Antibody – Mouse Monoclonal

Kinesin heavy chain member 2 is a kinesin-like motor protein. The kinesin-related proteins are involved in functions related to movements of organelles, microtubules, or chromosomes along microtubules. These functions include axonal transport, microtubule sliding during nuclear fusion or division, and chromosome disjunction during meiosis and early mitosis. The kinesins are tetramers composed of 2 heavy and 2 light chains. The N-terminal heavy chain sequences show similarity in all the kinesin-related proteins. The N-terminal part forms the motor domain, with the microtubule-binding region allowing the protein to slide along the microtubule. It also possesses an ATP-binding site allowing an ATPase activity that provides the energy required for the movement. Kinesin-like motor proteins are found in several vertebrate cell types but is strongly expressed in neuronal cells. In dividing cells it is required for bipolar spindle formation and chromosome segregation. In neuronal cells it is involved in neurite outgrowth.

Small volumes of anti-KNS2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS6129745 is an antibody targeting KNS2. Also known as Kinesin 2 (Kinesin-2, KNS2, HK2, KIF2, KIF2A, Kinesin Heavy Chain Member 2, Kinesin-like Protein KIF2A, Kinesin Heavy Chain Member 2A) (AP). Reactive in Human. Host: Mouse.