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OCT-1 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS613181

Mammalian kidney and liver are critical in maintaining physiological ionic environment. Kidney specializes in removing toxins, drugs, and other organic cations from the blood by an active process called "renal secretion". Functional studies have identified… More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
OCT-1, Polyclonal Antibody
Full Product Name
Anti - Oct-1 (Organic Cation Transporter 1)
Product Gene Name
anti-OCT-1 antibody
Product Synonym Names
Oct-1 (Organic Cation Transporter 1)
Clonality
Polyclonal
Isotype
IgG
Host
Host: Rabbit
Source: Rat
Species Reactivity
Rabbit, Rat
Form/Format
Serum
Supplied as a liquid, neat serum, 0.1% sodium azide, 40% glycerol.
Purity/Purification
Serum
Specificity
Recognizes rat Oct-1 (Organic Cation Transporter 1). The 21aa rat control peptide is 100% conserved in rat Oct1a (430aa), an alternatively spliced form of rat Oct1 (1). No significant sequence homology is detected with other Octs or OctNs. Species Sequence Homology
Preparation and Storage
May be stored at 4 degree C for short-term only. For long-term storage, aliquot and store at -20 degree C. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
61,154 Da
Chromosome Location
Chromosome: 6; NC_000006.11 (160542863..160579750). Location: 6q25.3
OMIM
602607
3D Structure
ModBase 3D Structure for O15245
Immunogen
Synthetic peptide consisting of 21aa within the cytoplasmic, C-terminus of rat Oct1 (KLH coupled).

Product Categories/Family for anti-OCT-1 antibody

Abs to Ion Channel
Applications Tested/Suitable for anti-OCT-1 antibody
ELISA, Western Blot
Application Notes for anti-OCT-1 antibody
Suitable for use in ELISA, Western Blot. Other applications not tested.
Dilution: Western Blot: 1:1000-1:5000 (ECL).
ELISA: 1:10,000-1:50,000. Control peptide can be used to coat ELISA plates at 1ug/ml.
Optimal dilutions to be determined by the researcher.

Product References and Citations for anti-OCT-1 antibody

• 1. Grundemann, D., et al., Nature (Lond.) 372: 549-552 (1994).
• 2. Zhang, L., et al., JBC 272: 16548 (1997).
• 3. Zhang, L., et al., Mol. Pharmacol. 51: 913 (1997).
• 4. Gorbuleve, V., et al., DNA Cell. Biol. 16: 871 (1997).
• 5. Koespell, H., Ann. Rev. Physiol. 60: 243-266 (1998, review).
• 6. Urakami, Y., et al., J. Pharmacol. Expt. Therap. 287: 800-805 (1998).
• 7. Meyer-Wentrup, F., et al., BBRC 248: 673-678 (1998).

Other Notes

Small volumes of anti-OCT-1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for OCT-1 purchase

MBS613181 is an antibody targeting OCT-1. Also known as Anti - Oct-1 (Organic Cation Transporter 1). Reactive in Rabbit, Rat. Host: Rabbit
Source: Rat.

Additional Details

NCBI/Uniprot data below describe general gene information for OCT-1. It may not necessarily be applicable to this product.

NCBI GI #
2343059
NCBI GeneID
6580
UniProt Primary Accession #
O15245
UniProt Secondary Accession #
O15395; Q9NQD4; A6NFF3; A8K1H2; C9JSU6
UniProt Related Accession #
O15245
NCBI Official Full Name
organic cation transporter 1
NCBI Official Synonym Full Names
solute carrier family 22 (organic cation transporter), member 1
NCBI Official Symbol
SLC22A1
NCBI Official Synonym Symbols
OCT1; HOCT1; oct1_cds
UniProt Protein Name
Solute carrier family 22 member 1
UniProt Synonym Protein Names
Organic cation transporter 1
Protein Family
POU domain, class 2, transcription factor
UniProt Gene Name
SLC22A1
UniProt Synonym Gene Names
OCT1
UniProt Entry Name
S22A1_HUMAN
NCBI Protein Information
solute carrier family 22 member 1; OTTHUMP00000017537; OTTHUMP00000238949; OTTHUMP00000238993; OTTHUMP00000238994; organic cation transporter 1

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-OCT-1 antibody

 Products by Pathway  Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Bile Secretion Pathway antibodies  Bile Secretion Pathway Diagram
 Organic Cation Transport Pathway antibodies  Organic Cation Transport Pathway Diagram
 Organic Cation/anion/zwitterion Transport Pathway antibodies  Organic Cation/anion/zwitterion Transport Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway antibodies  Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway Diagram

Diseases associated with anti-OCT-1 antibody

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >14 publications with OCT-1 and Neoplasms
 Drug Toxicity Antibodies  >12 publications with OCT-1 and Drug Toxicity
 Leukemia, Myelogenous, Chronic, BCR-ABL Positive Antibodies  >6 publications with OCT-1 and Leukemia, Myelogenous, Chronic, BCR-ABL Positive
 Diabetes Mellitus, Type 2 Antibodies  >5 publications with OCT-1 and Diabetes Mellitus, Type 2
 Biliary Tract Diseases Antibodies  >5 publications with OCT-1 and Biliary Tract Diseases
 Carcinoma Antibodies  >4 publications with OCT-1 and Carcinoma
 Liver Diseases Antibodies  >4 publications with OCT-1 and Liver Diseases
 Cholestasis Antibodies  >4 publications with OCT-1 and Cholestasis
 Kidney Diseases Antibodies  >4 publications with OCT-1 and Kidney Diseases
 Liver Neoplasms Antibodies  >3 publications with OCT-1 and Liver Neoplasms

Organs/Tissues associated with anti-OCT-1 antibody

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >40 publications with OCT-1 and Kidney
 Liver Antibodies  >40 publications with OCT-1 and Liver
 Brain Antibodies  >10 publications with OCT-1 and Brain
 Lung Antibodies  >9 publications with OCT-1 and Lung
 Muscle Antibodies  >5 publications with OCT-1 and Muscle
 Placenta Antibodies  >4 publications with OCT-1 and Placenta
 Mammary Gland Antibodies  >1 publications with OCT-1 and Mammary Gland
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