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MAPRE2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6137523

MBS6137523 is an antibody targeting MAPRE2. Also known as MAPRE2 (Microtubule-associated Protein RP/EB Family Member 2, APC-binding Protein EB2, End-binding Protein 2, EB2, RP1) APC. Reactive in Human. Host: Mouse. More details

$1155 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MAPRE2, Monoclonal Antibody
Full Product Name
MAPRE2 (Microtubule-associated Protein RP/EB Family Member 2, APC-binding Protein EB2, End-binding Protein 2, EB2, RP1) APC
Product Gene Name
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
4D7
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human MAPRE2.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
39.2 kDa (347aa), confirmed by MALDI-TOF
OMIM
605789
3D Structure
ModBase 3D Structure for Q15555
Immunogen
Partial recombinant corresponding to aa1-63 from human MAPRE2 (NP_055083) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
MPGPTQTLSPNGENNNDIIQDNNGTIIPFRKHTVRGERSYSWGMAVNVYSTSITQETMSRHD
Conjugate
APC

Product Categories/Family for anti-MAPRE2 antibody

Applications Tested/Suitable for anti-MAPRE2 antibody
ELISA (EIA), Immunofluorescence (IF), Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-MAPRE2 antibody
IF: 35ug/ml
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-MAPRE2 antibody

Western Blot detection against Immunogen (32.93kD).
Mouse Anti-MAPRE2 Monoclonal Antibody – Cat# MBS6137523

Western Blot (WB) of anti-MAPRE2 antibody

MAPRE2 monoclonal antibody Western Blot analysis of MAPRE2 expression in K-562.
Mouse Anti-MAPRE2 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6137523

Western Blot (WB) of anti-MAPRE2 antibody

Western Blot analysis of MAPRE2 expression in transfected 293T cell line by MAPRE2 monoclonal antibody Lane 1: MAPRE2 transfected lysate (37kD). Lane 2: Non-transfected lysate.
Mouse Anti-MAPRE2 Monoclonal Antibody, Western Blot (WB) – Cat# MBS6137523

Immunohistochemistry (IHC) of anti-MAPRE2 antibody

Immunoperoxidase of monoclonal antibody to MAPRE2 on formalin-fixed paraffin-embedded human colon. [antibody concentration 3ug/ml].
Mouse Anti-MAPRE2 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6137523

Immunofluorescence (IF) of anti-MAPRE2 antibody

Immunofluorescence of monoclonal antibody to MAPRE2 on HeLa cell. [antibody concentration 35ug/ml].
Mouse Anti-MAPRE2 Monoclonal Antibody, Immunofluorescence (IF) – Cat# MBS6137523

Other Notes

Small volumes of anti-MAPRE2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for MAPRE2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
microtubule-associated protein RP/EB family member 2 isoform 1
NCBI Official Synonym Full Names
microtubule associated protein RP/EB family member 2
NCBI Official Symbol
MAPRE2
NCBI Official Synonym Symbols
EB1; EB2; RP1; CSCSC2
UniProt Protein Name
Microtubule-associated protein RP/EB family member 2
UniProt Synonym Protein Names
APC-binding protein EB2; End-binding protein 2
UniProt Gene Name
MAPRE2
UniProt Synonym Gene Names
RP1; EB2
UniProt Entry Name
MARE2_HUMAN
NCBI Protein Information
microtubule-associated protein RP/EB family member 2

NCBI Summary for MAPRE2

The protein encoded by this gene shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. This protein is a microtubule-associated protein that is necessary for spindle symmetry during mitosis. It is thought to play a role in the tumorigenesis of colorectal cancers and the proliferative control of normal cells. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]
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UniProt Comments for MAPRE2

RP1: shares significant homology to the adenomatous polyposis coli (APC) protein-binding EB1 gene family. Its function is unknown; however, its homology suggests involvement in tumorigenesis of colorectal cancers and proliferative control of normal cells. This gene may belong to the intermediate/early gene family, involved in the signal transduction cascade downstream of the TCR.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 18q12.1

Cellular Component: microtubule cytoskeleton; cytoplasm

Molecular Function: microtubule binding

Biological Process: cell proliferation; mitosis; cell division; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-MAPRE2 antibody

 Reference Product  PubMed Publications
 CLASP2 antibody  >1 publications with MAPRE2 and CLASP2

Diseases associated with anti-MAPRE2 antibody

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