Chicken Anti-BRWD1 Polyclonal Antibody – Cat# MBS613929

BRWD1 Antibody – Chicken Polyclonal

Name: BRWD1 Antibody; Polyclonal; Chicken; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS613929
Price: 830 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS613929

MBS613929 is an antibody targeting BRWD1. Also known as WDR9 (WDR9, WD repeat domain 9, 90/3H1, FLJ11315, cAMP response element binding and beta-tranducin family-like). Reactive in Human. Host: Chicken. WDR9.3, a novel protein (57KD) from human chromosome 21. More details

$830 / 0.5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

WDR9 (BRWD1), Polyclonal Antibody

Full Product Name

WDR9 (WDR9, WD repeat domain 9, 90/3H1, FLJ11315, cAMP response element binding and beta-tranducin family-like)

Product Gene Name

anti-BRWD1 antibody

Product Synonym Names

Anti -WDR9 (WDR9, WD repeat domain 9, 90/3H1, FLJ11315, cAMP response element binding and beta-tranducin family-like)

Clonality

Polyclonal

Isotype

IgY

Host

Chicken

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.4, 0.02% sodium azide.

Purity/Purification

Purified
Purified

Specificity

Recognizes WDR9.3.

Preparation and Storage

May be stored at 4 degree C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Store at -20 degree C or colder. Aliquots are stable for at least 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

262,936 Da

Chromosome Location

chromosome: 21; Location: 21q22.2

3D Structure

ModBase 3D Structure for Q9NSI6

Immunogen

Purified WDR9.3 recombinant protein

Product Categories/Family for anti-BRWD1 antibody

Antibodies; Abs to WD Repeat Proteins

Applications Tested/Suitable for anti-BRWD1 antibody

Western Blot (WB)

Application Notes for anti-BRWD1 antibody

Can be used at 1:500-1:5000 for immunoblot testing.

Other Notes

Small volumes of anti-BRWD1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for BRWD1. It may not necessarily be applicable to this product.

NCBI GI #

14970564

NCBI GeneID

54014

UniProt Primary Accession #

Q9NSI6

UniProt Secondary Accession #

O43721; Q5R2V0; Q5R2V1; Q8TCV3; Q96QG9; Q96QH0; Q9NUK1; C9JK25

UniProt Related Accession #

Q5R2U4; Q5R2U5; Q5R2U6; Q5R2U7; Q5R2U8; Q5R2U9; Q6P2D1; Q9NSI6

NCBI Official Full Name

WDR9 protein, form B

NCBI Official Synonym Full Names

bromodomain and WD repeat domain containing 1

NCBI Official Symbol

BRWD1

NCBI Official Synonym Symbols

N143; WDR9; FLJ43918; C21orf107; BRWD1

UniProt Protein Name

Bromodomain and WD repeat-containing protein 1

UniProt Synonym Protein Names

WD repeat-containing protein 9

Protein Family

Bromodomain and WD repeat-containing protein

UniProt Gene Name

BRWD1

UniProt Synonym Gene Names

C21orf107; WDR9

UniProt Entry Name

BRWD1_HUMAN

NCBI Protein Information

bromodomain and WD repeat-containing protein 1; WD repeat domain 9; transcriptional unit N143; WD repeat protein WDR9-form2; WD repeat-containing protein 9; cAMP response element binding and beta-tranducin family-like

NCBI Summary for BRWD1

This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats, and the function of this protein is not known. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates 3 transcript variants diverging at the 3' ends. [provided by RefSeq]

UniProt Comments for BRWD1

WDR9: an ubiquitously expressed WD40 repeat protein that may be a transcriptional activator and be involved in chromatin remodeling. Interacts with SMARCA4. WD40 repeats are found in a number of eukaryotic proteins that coordinate multi-protein complex assemblies. WD40 proteins are implicated in many functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly. Three alternatively spliced human isoforms have been described.

Protein type: Transcription factor

Chromosomal Location of Human Ortholog: 21q22.2

Cellular Component: cytoplasm; nucleolus; nucleus

Biological Process: regulation of transcription from RNA polymerase II promoter; regulation of cell shape; transcription, DNA-dependent; cytoskeleton organization and biogenesis

Research Articles on BRWD1

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
2. Observational study and genome-wide association study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
3. isolation and characterization of the gene located in the Down Syndrome critical region-2 of chromosome 21

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with anti-BRWD1 antibody

Disease Name	Pubmed Publications
Necrosis Antibodies	>1 publications with BRWD1 and Necrosis