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HDAC7A Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6142244

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle… More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
HDAC7A, Monoclonal Antibody
Full Product Name
HDAC7A (Histone Deacetylase 7, HD7, Histone Deacetylase 7A, HD7a, HDAC7A, DKFZp586J0917, DKFZP586J0917, FLJ99588) (Biotin)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2b,k
Clone Number
2B11-1C1
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human HDAC7A.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
66,187 Da
Immunogen
Full length recombinant corresponding to aa1-277 from human HDAC7A (AAH06453) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
MGFCFFNSVAIACRQLQQQSKASKILIVDWDVHHGNGTQQTFYQDPSVLYISLHRHDDGNFFPGSGAVDEVGAGSGEGFNVNVAWAGGLDPPMGDPEYLAAFRIVVMPIAREFSPDLVLVSAGFDAAEGHPAPLGGYHVSAKCFGYMTQQLMNLAGGAVVLALEGGHDLTAICDASEACVAALLGNRVDPLSEEGWKQKPNLNAIRSLEAVIRVHSKYWGCMQRLASCPDSWVPRVPGADKEEVEAVTALASLSVGILAEDRPSEQLVEEEEPMNL
Conjugate
Biotin

Product Categories/Family for anti-HDAC7A antibody

Applications Tested/Suitable for anti-HDAC7A antibody
ELISA (EIA), Western Blot (WB)
Application Notes for anti-HDAC7A antibody
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-HDAC7A antibody

Western Blot detection against Immunogen (56.47kD).
Mouse Anti-HDAC7A Monoclonal Antibody – Cat# MBS6142244

Western Blot (WB) of anti-HDAC7A antibody

HDAC7A monoclonal antibody, Western Blot analysis of HDAC7A expression in K-562.
Mouse Anti-HDAC7A Monoclonal Antibody, Western Blot (WB) – Cat# MBS6142244

Western Blot (WB) of anti-HDAC7A antibody

Western Blot analysis of HDAC7A expression in transfected 293T cell line by HDAC7A monoclonal antibody. Lane 1: HDAC7A transfected lysate (29.6kD). Lane 2: Non-transfected lysate.
Mouse Anti-HDAC7A Monoclonal Antibody, Western Blot (WB) – Cat# MBS6142244

Western Blot (WB) of anti-HDAC7A antibody

Western blot analysis of HDAC7A over-expressed 293 cell line, cotransfected with HDAC7A Validated Chimera RNAi (Lane 2) or non-transfected control (Lane 1). Blot probed with HDAC7A monoclonal antibody. GAPDH (36.1kD) used as specificity and loading control.
Mouse Anti-HDAC7A Monoclonal Antibody, Western Blot (WB) – Cat# MBS6142244

Other Notes

Small volumes of anti-HDAC7A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HDAC7A purchase

MBS6142244 is an antibody targeting HDAC7A. Also known as HDAC7A (Histone Deacetylase 7, HD7, Histone Deacetylase 7A, HD7a, HDAC7A, DKFZp586J0917, DKFZP586J0917, FLJ99588) (Biotin). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for HDAC7A. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI Related Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Homo sapiens histone deacetylase 7, mRNA
NCBI Official Synonym Full Names
histone deacetylase 7
NCBI Official Symbol
HDAC7
NCBI Official Synonym Symbols
HD7; HD7A; HDAC7A
NCBI Protein Information
histone deacetylase 7

NCBI Summary for HDAC7A

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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