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PRRG1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6143772

MBS6143772 is an antibody targeting PRRG1. Also known as PRRG1 (PRGP1, TMG1, Transmembrane gamma-carboxyglutamic Acid Protein 1, Proline-rich gamma-carboxyglutamic Acid Protein 1) (Biotin). Reactive in Human. Host: Mouse. More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PRRG1, Monoclonal Antibody
Full Product Name
PRRG1 (PRGP1, TMG1, Transmembrane gamma-carboxyglutamic Acid Protein 1, Proline-rich gamma-carboxyglutamic Acid Protein 1) (Biotin)
Product Gene Name
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
1C7
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Purity/Purification
Purified by Protein A Affinity Chromatography.
Specificity
Recognizes human PRRG1.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
25kDa
OMIM
604428
3D Structure
ModBase 3D Structure for O14668
Immunogen
Partial recombinant corresponding to aa22-82, from human PRRG1 (NP_000941) with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
NGFFEEIRQGNIERECKEEFCTFEEAREAFENNEKTKEFWSTYTKAQQGESNRGSDWFQF
Conjugate
Biotin
Applications Tested/Suitable for anti-PRRG1 antibody
ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes for anti-PRRG1 antibody
IHC-P: 3ug/ml
Applications are based on unconjugated antibody.

Testing Data of anti-PRRG1 antibody

Immunoperoxidase of monoclonal antibody to PRRG1 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 3ug/ml].
Mouse Anti-PRRG1 Monoclonal Antibody – Cat# MBS6143772

Other Notes

Small volumes of anti-PRRG1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PRRG1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
transmembrane gamma-carboxyglutamic acid protein 1 isoform 1
NCBI Official Synonym Full Names
proline rich and Gla domain 1
NCBI Official Symbol
PRRG1
NCBI Official Synonym Symbols
PRGP1
UniProt Protein Name
Transmembrane gamma-carboxyglutamic acid protein 1
UniProt Synonym Protein Names
Proline-rich gamma-carboxyglutamic acid protein 1
UniProt Gene Name
PRRG1
UniProt Synonym Gene Names
PRGP1; TMG1; Proline-rich Gla protein 1
UniProt Entry Name
TMG1_HUMAN
NCBI Protein Information
transmembrane gamma-carboxyglutamic acid protein 1

NCBI Summary for PRRG1

This gene encodes a vitamin K-dependent, gamma-carboxyglutamic acid (Gla)-containing, single-pass transmembrane protein. This protein contains a Gla domain at the N-terminus, preceded by a propeptide sequence required for post-translational gamma-carboxylation of specific glutamic acid residues by a vitamin K-dependent gamma-carboxylase. The C-terminus is proline-rich containing PPXY and PXXP motifs found in a variety of signaling and cytoskeletal proteins. This gene is highly expressed in the spinal cord. Several alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2010]
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UniProt Comments for PRRG1

Subcellular location: Membrane; Single-pass type I membrane protein

Potential.

Tissue specificity: Highly expressed in the spinal cord.

Post-translational modification: Gla residues are produced after subsequent post-translational modifications of glutamate by a vitamin K-dependent gamma-carboxylase.

Sequence similarities: Contains 1 Gla (gamma-carboxy-glutamate) domain.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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